Oncological diseases have currently reached an epidemic scale, especially in industrialized
countries. Such a situation has prompted complex studies in medicinal chemistry focused on …

Growing epidemiological evidence indicates an association between obesity, type 2
diabetes, and certain cancers, suggesting the existence of common underlying mechanisms …

A library of twelve hybrid molecules containing Indole‐Thiazolidinedione‐Triazole moieties
were synthesized by following a series of N‐benzylation, Knoevenagel condensation and …

Diabetes mellitus (DM) is a metabolic disorder majorly arising from the pathophysiology of
the pancreas manifested as a decline in the insulin production or the tissue's resistance to …

In search of new antidiabetic agents, heterocyclic compounds containing 3, 5-Substituted
thiazolidinedione moieties were synthesized through a concise three-step reaction process …

Developing new anti-tyrosinase drugs seems crucial for the medical and industrial fields
since irregular melanin synthesis is linked to the resurgence of several skin conditions …

Pyridine-based ring structures are widely employed in drug design due to their significant
impact on pharmacological activity, resulting in the development of various broad-spectrum …

Cancer is a complex and heterogeneous disease and is still one of the leading causes of
morbidity and mortality worldwide, mostly as the population ages. Despite the encouraging …

Worldwide, breast cancer is still a leading cause of cancer death in women. Indeed, over the
years, several anti-breast cancer drugs have been developed; however, the complex …

Cancer remains one of the most pressing global public health challenges. While
chemotherapy has long been a cornerstone of cancer treatment, its inability to distinguish …