Ultra-high-resolution ion mobility spectrometry—current instrumentation, limitations, and future developments

AT Kirk, A Bohnhorst, CR Raddatz, M Allers… - Analytical and …, 2019 - Springer
With recent advances in ionization sources and instrumentation, ion mobility spectrometers
(IMS) have transformed from a detector for chemical warfare agents and explosives to a …

Ion gating in ion mobility spectrometry: Principles and advances

C Chen, M Tabrizchi, H Li - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
Linear drift tube ion mobility spectrometry (DTIMS) is widely used in standalone and
hyphenated IMS instruments for detecting trace chemical compounds. As a temporal …

High-resolution high kinetic energy ion mobility spectrometer based on a low-discrimination tristate ion shutter

AT Kirk, D Grube, T Kobelt, C Wendt… - Analytical …, 2018 - ACS Publications
High kinetic energy ion mobility spectrometry (HiKE-IMS) allows for sensitive trace gas
analysis within seconds, mitigating many disadvantages of standard ion mobility …

Miniaturized ion mobility spectrometer with a dual-compression tristate ion shutter for on-site rapid screening of fentanyl drug mixtures

H Chen, C Chen, W Huang, M Li, Y Xiao… - Analytical …, 2019 - ACS Publications
The hidden presence of fentanyl and new psychoactive substances in established illicit
drugs has led to a great number of unintentional fatal overdoses, justifying the urgent need …

How to Improve the Resolving Power of Compact Electrospray Ionization Ion Mobility Spectrometers

C Thoben, CR Raddatz, A Tataroglu, T Kobelt… - Analytical …, 2023 - ACS Publications
Every drift tube ion mobility spectrometer (IMS) has an optimum drift voltage to reach
maximum resolving power. This optimum depends, among other things, on the temporal and …

Electrospray ionization ion mobility spectrometer with new tristate ion gating for improved sensitivity for compounds with lower ion mobility

C Thoben, CR Raddatz, M Lippmann… - Talanta, 2021 - Elsevier
An electrospray is a dispersed nebula of charged droplets produced under the influence of a
strong electric field. The charged droplets subsequently result in ions in the gas phase …

Pushing the resolving power of tyndall–powell gate ion mobility spectrometry over 100 with no sensitivity loss for multiple ion species

C Chen, H Chen, H Li - Analytical chemistry, 2017 - ACS Publications
Ion gate is a key buildup for drift tube ion mobility spectrometry (IMS) and its combination
with mass spectrometry. Bradbury–Nielsen gate, as the most commonly used ion gate in …

Resolution enhancement of ion mobility spectrometry by improving the three-zone properties of the Bradbury-Nielsen gate

Y Du, W Wang, H Li - Analytical chemistry, 2012 - ACS Publications
A simple space compression-dispersion model for ion transport at ambient pressure was
mathematically established. On the basis of this model and aided by SIMION simulation, a …

Bradbury–Nielsen–gate–grid structure for further enhancing the resolution of ion mobility spectrometry

Y Du, W Wang, H Li - Analytical chemistry, 2012 - ACS Publications
In our previous work we proposed a three-zone theory for the Bradbury–Nielsen (BN) gate
and proved with a grid–BN structure ion mobility drift tube that enhancements of the three …

Developmental accumulation of thebaine and some gene transcripts in different organs of Papaver bracteatum

M Rezaei, MR Naghavi, AH Hoseinzade… - Industrial Crops and …, 2016 - Elsevier
Noted as a rich source of thebaine and a potential alternative to Papaver somniferum for
production of codeine and some semi-synthetic antagonist drugs (namely naloxone and …