[HTML][HTML] Gut microbiota-dependent marker TMAO in promoting cardiovascular disease: inflammation mechanism, clinical prognostic, and potential as a therapeutic …

S Yang, X Li, F Yang, R Zhao, X Pan, J Liang… - Frontiers in …, 2019 - frontiersin.org
Cardiovascular disease (CVD) is the leading cause of death worldwide, especially in
developed countries, and atherosclerosis (AS) is the common pathological basis of many …

Endothelial dysfunction and hypertension

D Konukoglu, H Uzun - Hypertension: from basic research to clinical …, 2017 - Springer
In the past, endothelium was thought to be only a mechanical barrier. Today, endothelium is
known to be a tissue regulating vascular tone, cell growth and the interaction between the …

[HTML][HTML] Identification of immune cell infiltration and diagnostic biomarkers in unstable atherosclerotic plaques by integrated bioinformatics analysis and machine …

J Wang, Z Kang, Y Liu, Z Li, Y Liu, J Liu - Frontiers in Immunology, 2022 - frontiersin.org
Objective The decreased stability of atherosclerotic plaques increases the risk of ischemic
stroke. However, the specific characteristics of dysregulated immune cells and effective …

[HTML][HTML] The aging risk and atherosclerosis: a fresh look at arterial homeostasis

T Head, S Daunert, PJ Goldschmidt-Clermont - Frontiers in genetics, 2017 - frontiersin.org
A considerable volume of research over the last decade has focused on understanding the
fundamental mechanisms for the progression of atherosclerosis—the underlying cause for …

Gut microbiota-derived metabolites in CRC progression and causation

N Dalal, R Jalandra, N Bayal, AK Yadav… - Journal of Cancer …, 2021 - Springer
Background Based on recent research reports, dysbiosis and improper concentrations of
microbial metabolites in the gut may result into the carcinogenesis of colorectal cancer …

[HTML][HTML] The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis

S Geng, K Chen, R Yuan, L Peng, U Maitra… - Nature …, 2016 - nature.com
Sustained low-grade inflammation mediated by non-resolving inflammatory monocytes has
long been suspected in the pathogenesis of atherosclerosis; however, the molecular …

Lipoic acid: its antioxidant and anti-inflammatory role and clinical applications

F Andrea Moura, K Queiroz de Andrade… - Current Topics in …, 2015 - ingentaconnect.com
Lipoic acid (LA) is an antioxidant able to produce its effects in aqueous or lipophilic
environments. Lipoate is the conjugate base of lipoic acid, and the most prevalent form of LA …

[PDF][PDF] Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates

JA Mattison, M Wang, M Bernier, J Zhang, SS Park… - Cell metabolism, 2014 - cell.com
Central arterial wall stiffening, driven by a chronic inflammatory milieu, accompanies arterial
diseases, the leading cause of cardiovascular (CV) morbidity and mortality in Western …

[HTML][HTML] Therapeutic potential of quercetin as an antiatherosclerotic agent in atherosclerotic cardiovascular disease: a review

Q Deng, XX Li, Y Fang, X Chen, J Xue - … -Based Complementary and …, 2020 - hindawi.com
Atherosclerotic cardiovascular disease (ASCVD) is one of the diseases with the highest
morbidity and mortality globally. It causes a huge burden on families and caregivers and …

Mesenchymal stem cell-derived exosomal miR-21a-5p promotes M2 macrophage polarization and reduces macrophage infiltration to attenuate atherosclerosis

J Ma, L Chen, X Zhu, Q Li, L Hu… - Acta biochimica et …, 2021 - academic.oup.com
Atherosclerosis (AS) is the main pathological basis for ischemic cardiovascular and
cerebrovascular diseases. Mesenchymal stem cell (MSC)-derived exosomes have the …