Pathologies related to the cardiovascular system are the leading causes of death worldwide.
One of the main treatments is conventional surgery with autologous transplants. Although …

Vascular tissue engineering is an area of regenerative medicine that attempts to create
functional replacement tissue for defective segments of the vascular network. One approach …

Background Tissue-engineered vascular grafts (TEVGs) have the potential to advance the
surgical management of infants and children requiring congenital heart surgery by creating …

Stenosis is the primary complication of current tissue-engineered vascular grafts used in
pediatric congenital cardiac surgery. Murine models provide considerable insight into the …

The modification of biomaterials to comply with clinically employed monitoring techniques is
a promising strategy to support clinical translation in regenerative medicine. Here …

Globally, millions of patients are affected by myocardial infarction or lower limb
gangrene/amputation due to atherosclerosis. Available surgical treatment based on vein …

Thrombogenicity poses a challenge to the clinical translation of engineered grafts.
Previously, small-diameter vascular grafts (sdVG) composed of fibrin hydrogel microfiber …

Despite current advancements in chemotherapy, immunotherapy and targeted treatments,
the potential for major adverse cardiovascular events, regardless of previous cardiac history …

Congenital heart disease (CHD) represents a large clinical burden, representing the most
common cause of birth defect-related death in the newborn. The mainstay of treatment for …

The mechanism of action underlying the intriguing prominent bioactivity of urinary bladder
matrix (UBM) for in situ tissue regeneration of soft tissue defects remains to be elucidated. It …