Advances in microfluidics for single red blood cell analysis
GV Grigorev, AV Lebedev, X Wang, X Qian… - Biosensors, 2023 - mdpi.com
The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …
Blood plasma self-separation technologies during the self-driven flow in microfluidic platforms
Blood plasma is the most commonly used biofluid in disease diagnostic and biomedical
analysis due to it contains various biomarkers. The majority of the blood plasma separation …
analysis due to it contains various biomarkers. The majority of the blood plasma separation …
[HTML][HTML] Analysis of red blood cell partitioning at bifurcations in simulated microvascular networks
Partitioning of red blood cells (RBCs) at vascular bifurcations has been studied over many
decades using in vivo, in vitro, and theoretical models. These studies have shown that RBCs …
decades using in vivo, in vitro, and theoretical models. These studies have shown that RBCs …
[HTML][HTML] In vitro investigations of red blood cell phase separation in a complex microchannel network
Microvascular networks feature a complex topology with multiple bifurcating vessels.
Nonuniform partitioning (phase separation) of red blood cells (RBCs) occurs at diverging …
Nonuniform partitioning (phase separation) of red blood cells (RBCs) occurs at diverging …
Abnormal morphology biases hematocrit distribution in tumor vasculature and contributes to heterogeneity in tissue oxygenation
Oxygen heterogeneity in solid tumors is recognized as a limiting factor for therapeutic
efficacy. This heterogeneity arises from the abnormal vascular structure of the tumor, but the …
efficacy. This heterogeneity arises from the abnormal vascular structure of the tumor, but the …
Glomerular microcirculation: Implications for diabetes, preeclampsia, and kidney injury
MS Goligorsky - Acta Physiologica, 2023 - Wiley Online Library
This review outlines the features of tandem regulation of glomerular microcirculation by
autoregulatory mechanisms and intraglomerular redistribution of blood flow. Multiple points …
autoregulatory mechanisms and intraglomerular redistribution of blood flow. Multiple points …
Red blood cell lingering modulates hematocrit distribution in the microcirculation
The distribution of red blood cells (RBCs) in the microcirculation determines the oxygen
delivery and solute transport to tissues. This process relies on the partitioning of RBCs at …
delivery and solute transport to tissues. This process relies on the partitioning of RBCs at …
The coronary capillary bed and its role in blood flow and oxygen delivery: A review
RJ Tomanek - The Anatomical Record, 2022 - Wiley Online Library
The assumption that the coronary capillary blood flow is exclusively regulated by
precapillary vessels is not supported by recent data. Rather, the complex coronary capillary …
precapillary vessels is not supported by recent data. Rather, the complex coronary capillary …
A homogenized two-phase computational framework for meso-and macroscale blood flow simulations
Abstract Background and Objective Owing to the complexity of physics linked with blood flow
and its associated phenomena, appropriate modeling of the multi-constituent rheology of …
and its associated phenomena, appropriate modeling of the multi-constituent rheology of …
PyOIF: Computational tool for modelling of multi-cell flows in complex geometries
I Jančigová, K Kovalčíková, R Weeber… - PLOS Computational …, 2020 - journals.plos.org
A user ready, well documented software package PyOIF contains an implementation of a
robust validated computational model for cell flow modelling. The software is capable of …
robust validated computational model for cell flow modelling. The software is capable of …