Functions of bromodomain-containing proteins and their roles in homeostasis and cancer

T Fujisawa, P Filippakopoulos - Nature reviews Molecular cell biology, 2017 - nature.com
Bromodomains (BRDs) are evolutionarily conserved protein–protein interaction modules
that are found in a wide range of proteins with diverse catalytic and scaffolding functions and …

NUT carcinoma: clinicopathologic features, molecular genetics and epigenetics

V Moreno, K Saluja, S Pina-Oviedo - Frontiers in Oncology, 2022 - frontiersin.org
Nuclear protein in testis (NUT) carcinoma is a rare, highly aggressive, poorly differentiated
carcinoma occurring mostly in adolescents and young adults. This tumor usually arises from …

NUT carcinoma of the salivary glands: clinicopathologic and molecular analysis of 3 cases and a survey of NUT expression in salivary gland carcinomas

A Agaimy, I Fonseca, C Martins, K Thway… - The American journal …, 2018 - journals.lww.com
NUT carcinoma (NC) represents a rare subset of highly aggressive poorly differentiated
carcinomas characterized by rearrangement of the NUT (aka NUTM1, nuclear protein in …

The landscape of gene fusions and somatic mutations in salivary gland neoplasms–implications for diagnosis and therapy

MK Andersson, G Stenman - Oral oncology, 2016 - Elsevier
Recent studies of the genomic landscape of salivary gland tumors have provided important
insights into the molecular pathogenesis of these tumors. The most consistent alterations …

An update on head and neck cancer: new entities and their histopathology, molecular background, treatment, and outcome

S Andreasen, K Kiss, LH Mikkelsen, HI Channir… - Apmis, 2019 - Wiley Online Library
The head and neck region harbor numerous specialized tissues of all lineages giving rise to
a plethora of different malignancies. In recent years, new types and subtypes of cancer has …

Primary Thyroid NUT Carcinoma With High PD-L1 Expression and Novel Massive IGKV Gene Fusions: A Case Report With Treatment Implications and Literature …

J Zhou, M Duan, Q Jiao, C Chen, A Xing, P Su… - Frontiers in …, 2022 - frontiersin.org
Background Nuclear protein in testis (NUT) carcinoma (NC) is a rare and aggressive
undifferentiated carcinoma that typically arises from midline supradiaphragmatic structures …

Prevalence of NUT carcinoma in head and neck: analysis of 362 cases with literature review

T Lee, J Cho, CH Baek, YI Son, HS Jeong… - Head & …, 2020 - Wiley Online Library
Background Nuclear protein in testis (NUT) carcinoma is a poorly differentiated carcinoma
defined by the presence of NUT gene rearrangement. In the head and neck, the true …

NUT midline carcinoma of the larynx: an international series and review of the literature

H Hellquist, CA French, JA Bishop… - …, 2017 - Wiley Online Library
Aims NUT midline carcinoma (NMC) is a rare undifferentiated and aggressive carcinoma
that locates characteristically to the midline of the head and neck, and mediastinum. NMC is …

NUT carcinoma of the submandibular gland: a case at this uncommon site with review of the literature

V Moreno, CA French, T Guo, H Zhu, S Zhang… - Head and Neck …, 2022 - Springer
Nuclear protein in testis (NUT) carcinoma is a rare, highly aggressive, undifferentiated
carcinoma that harbors a characteristic rearrangement of the NUTM1 gene. The majority …

Tumors of the sublingual gland: a national clinicopathologic study of 29 cases

S Andreasen, K Bjørndal, TK Agander, I Wessel… - European Archives of …, 2016 - Springer
Tumors of the salivary glands are a heterogeneous group of diseases most often originating
in the major salivary glands. Only a minor proportion of mainly malignant tumors arise in the …