[HTML][HTML] Cheminformatics strategies unlock Marburg virus VP35 inhibitors from natural compound library

IM Alsaady, LH Bajrai, TA Alandijany, HS Gattan… - Viruses, 2023 - mdpi.com
The Ebola virus and its close relative, the Marburg virus, both belong to the family Filoviridae
and are highly hazardous and contagious viruses. With a mortality rate ranging from 23% to …

[HTML][HTML] Structural and dynamical basis of VP35-RBD inhibition by marine fungi compounds to combat marburg virus infection

AS Alawam, HS Alawam, MM Alshahrani… - Marine Drugs, 2024 - mdpi.com
The Marburg virus (MBV), a deadly pathogen, poses a serious threat to world health due to
the lack of effective treatments, calling for an immediate search for targeted and efficient …

[PDF][PDF] Emergence of Marburg virus disease in West Africa amid COVID-19 and Ebola: efforts, challenges, and recommendations to prevent the next public health crisis

JA Lawrence, MH Ul Rasool, C Parikh… - J Infect Dis …, 2022 - researchgate.net
Marburg virus disease (MVD) is a type of hemorrhagic fever caused by a genetically unique
animal-borne RNA virus of the filovirus family-like Ebola virus. The African fruit bat is the …

[HTML][HTML] Marburg virus is nature's wake-up call: A bird's-eye view

S Boora, S Kaushik, JP Yadav, S Kaushik… - Medicine in …, 2024 - Elsevier
Marburg virus (MARV), a member of Filoviridae family, is notorious for causing Marburg virus
disease (MVD), one of the deadliest known infectious diseases. Over the past five decades …

[HTML][HTML] Antifungal potential of marine bacterial compounds in inhibiting Candida albicans Yck2 to overcome echinocandin resistance: a molecular dynamics study

MM Alshahrani - Frontiers in Pharmacology, 2024 - frontiersin.org
Candida albicans (C. albicans), a common fungal pathogen, poses a significant threat to
immunocompromised individuals, particularly due to the emergence of resistance against …

Identification of novel inhibitors against VP40 protein of Marburg virus by integrating molecular modeling and dynamics approaches

M Saeed, MA Alamri, MAR Rashid… - Journal of …, 2023 - Taylor & Francis
Marburg virus (MV) is a highly etiological agent of haemorrhagic fever in humans and has
spread across the world. Its outbreaks caused a 23–90% human death rate. However, there …

[HTML][HTML] Molecular modelling and simulation techniques to investigate the effects of fungal metabolites on the SARS-CoV-2 RdRp protein inhibition

UM Muddapur, S Badiger, IA Shaikh… - Journal of King Saud …, 2022 - Elsevier
Various protein/receptor targets have been discovered through in-silico research. They are
expanding rapidly due to their extensive advantage of delivering new drug candidates more …

APPLICATION OF NEUTROSOPHIC SET TRANSFER LEARNING APPROACH TO CLASSIFY MARBURG-VIRUS

A Sebasthiyar, M Kavitha - Obstetrics and …, 2024 - obstetricsandgynaecologyforum.com
Background: This study aimed to People all throughout the Africa are affected significantly
by the Marburg-Virus. Preventing and classify the republic of Africa and local spread of this …