Abstract Modern nosologies (eg, International Classification of Diseases, 11th edition [ICD-
11], Diagnostic and Statistical Manual of Mental Disorders, 5th edition [DSM–5]) for alcohol …

Background Substance use disorder (SUD) remains a significant public health issue. A
greater understanding of how genes and environment interact to regulate phenotypes …

Sleep bruxism (SB) and obstructive sleep apnea (OSA) are co-occurring sleep conditions.
The study aimed to evaluate the association of selected single-nucleotide polymorphisms …

Neurotrophins have been implicated in the pathophysiology of many neuropsychiatric
diseases. Brain-derived neurotrophic factor (BDNF) is the most abundant and widely …

Alcoholism is a complex brain disease characterized by three distinct stages of the addiction
cycle that manifest as neuroadaptive changes in the brain. One such stage of the addiction …

Background Adolescence represents a period of development during which critical
biological, as well as social and cognitive, changes occur that are necessary for the …

Parkinson's disease (PD) is a common and severe movement disorder. Differences in
telomere length (TL) have been reported as possible risk factors for several neuropsychiatric …

Alcohol use disorder (AUD) exacts an immense toll on individuals, families, and society.
Genetic factors determine up to 60% of an individual's risk of developing problematic alcohol …

Major gene effects on traits associated with substance use disorders are rare. Previous
findings in methamphetamine drinking (MADR) lines of mice, bred for high or low voluntary …

Monoamine oxidases, both MAO-A and MAO-B, have been implicated in personality traits
and complex behaviour, including drug use. Findings supporting the involvement of MAO-A …