Medicinal attributes of 1, 2, 3-triazoles: Current developments
Triazoles are important five-membered heterocyclic scaffold due to their extensive biological
activities. This framework can be readily obtained in good to excellent yields on the …
activities. This framework can be readily obtained in good to excellent yields on the …
Triazole derivatives and their antiplasmodial and antimalarial activities
XM Chu, C Wang, WL Wang, LL Liang, W Liu… - European journal of …, 2019 - Elsevier
Malaria, caused by protozoan parasites of the genus Plasmodium especially by the most
prevalent parasite Plasmodium falciparum, represents one of the most devastating and …
prevalent parasite Plasmodium falciparum, represents one of the most devastating and …
Chalcone hybrids as privileged scaffolds in antimalarial drug discovery: A key review
Malaria remains a serious worldwide health danger and massive economic trouble to
disease-endemic nations. Presently, 250 million of malarial cases are expected worldwide …
disease-endemic nations. Presently, 250 million of malarial cases are expected worldwide …
Recent accomplishments on the synthetic/biological facets of pharmacologically active 1H-1, 2, 3-triazoles
The continuous demand of medicinally important scaffolds has prompted the synthetic
chemists to identify simple and efficient routes for their synthesis. 1H-1, 2, 3-triazole …
chemists to identify simple and efficient routes for their synthesis. 1H-1, 2, 3-triazole …
Current development of 1, 2, 3-triazole derived potential antimalarial scaffolds: Structure activity relationship (SAR) and bioactive compounds
Malaria is among one of the most devastating and deadliest parasitic disease in the world
claiming millions of lives every year around the globe. It is a mosquito-borne infectious …
claiming millions of lives every year around the globe. It is a mosquito-borne infectious …
Quinoline-based hybrid compounds with antimalarial activity
The application of quinoline-based compounds for the treatment of malaria infections is
hampered by drug resistance. Drug resistance has led to the combination of quinolines with …
hampered by drug resistance. Drug resistance has led to the combination of quinolines with …
Ferrocene-appended pharmacophores: An exciting approach for modulating the biological potential of organic scaffolds
Two exemplary contributions of organometallics in medicinal chemistry, ferroquine and
ferrocifen, which exhibit excellent anti-plasmodial and anti-cancer activities, respectively …
ferrocifen, which exhibit excellent anti-plasmodial and anti-cancer activities, respectively …
A review of synthetic bioactive tetrahydro-β-carbolines: A medicinal chemistry perspective
J Wang, F Gong, T Liang, Z Xie, Y Yang, C Cao… - European Journal of …, 2021 - Elsevier
Abstract 1, 2, 3, 4-Tetrahydro-β-carboline (THβC) scaffold is widespread in many natural
products (NPs) and synthetic compounds which show a variety of pharmacological activities …
products (NPs) and synthetic compounds which show a variety of pharmacological activities …
Ferrocene derivatives as anti-infective agents
BS Ludwig, JDG Correia, FE Kühn - Coordination Chemistry Reviews, 2019 - Elsevier
Infectious diseases like malaria, tuberculosis or HIV are among the leading causes of death
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …
Perspectives of medicinally privileged chalcone based metal coordination compounds for biomedical applications
Recent clinical reports have highlighted the increasing occurrence of drug resistance of
known therapeutics. Particularly, antibiotic resistant microorganisms and multidrug …
known therapeutics. Particularly, antibiotic resistant microorganisms and multidrug …