[HTML][HTML] Promising drug targets and associated therapeutic interventions in Parkinson's disease

SN Rai, P Singh, R Varshney… - Neural regeneration …, 2021 - journals.lww.com
Parkinson's disease (PD) is one of the most debilitating brain diseases. Despite the
availability of symptomatic treatments, response towards the health of PD patients remains …

[HTML][HTML] Antioxidant and neuroprotective effects of caffeine against Alzheimer's and Parkinson's disease: Insight into the role of Nrf-2 and A2AR signaling

M Ikram, TJ Park, T Ali, MO Kim - Antioxidants, 2020 - mdpi.com
This paper reviews the results of studies conducted on the role of caffeine in the
management of different neurological disorders, such as Parkinson's disease (PD) and …

[HTML][HTML] Therapeutic application of betalains: A review

E Madadi, S Mazloum-Ravasan, JS Yu, JW Ha… - Plants, 2020 - mdpi.com
Anthocyanins, betalains, riboflavin, carotenoids, chlorophylls and caramel are the basic
natural food colorants used in modern food manufacture. Betalains, which are composed of …

Biological effects of red beetroot and betalains: A review

E Hadipour, A Taleghani… - Phytotherapy …, 2020 - Wiley Online Library
Over the past few years, the use of natural substances as protective or therapeutic agents
has gained much attention worldwide. Recent modern studies have shown a variety of …

[HTML][HTML] Oxidative stress factors in Parkinson's disease

J Dorszewska, M Kowalska, M Prendecki… - Neural regeneration …, 2021 - journals.lww.com
Parkinson's disease (PD) is the second most common cause of neurodegeneration. Over the
last two decades, various hypotheses have been proposed to explain the etiology of PD …

Brain drug delivery and neurodegenerative diseases: Polymeric PLGA-based nanoparticles as a forefront platform

M Pinto, V Silva, S Barreiro, R Silva, F Remião… - Ageing Research …, 2022 - Elsevier
The discovery of effective drugs for the treatment of neurodegenerative disorders (NDs) is a
deadlock. Due to their complex etiology and high heterogeneity, progresses in the …

[HTML][HTML] Role of exosomes in the pathogenesis of inflammation in Parkinson's disease

KL Li, HY Huang, H Ren, XL Yang - Neural regeneration research, 2022 - journals.lww.com
Inflammatory responses, including glial cell activation and peripheral immune cell infiltration,
are involved in the pathogenesis of Parkinson's disease (PD). These inflammatory …

[HTML][HTML] Effect of Parkinson's disease and related medications on the composition of the fecal bacterial microbiota

S Weis, A Schwiertz, MM Unger, A Becker… - npj Parkinson's …, 2019 - nature.com
Parkinson's disease (PD) is one of the most common neurodegenerative disorders. PD
patients suffer from gastrointestinal dysfunctions and alterations of the autonomous nervous …

[HTML][HTML] Insights into the effects of mesenchymal stem cell-derived secretome in Parkinson's disease

M d'Angelo, A Cimini, V Castelli - International Journal of Molecular …, 2020 - mdpi.com
Mesenchymal stem cell (MSC)-derived secretome demonstrated therapeutic effects like
those reported after MSCs transplantation. MSC-derived secretome may avoid various side …

Biophenols: Enzymes (β-secretase, Cholinesterases, histone deacetylase and tyrosinase) inhibitors from olive (Olea europaea L.)

SH Omar, CJ Scott, AS Hamlin, HK Obied - Fitoterapia, 2018 - Elsevier
The focus of this study was on inhibition of enzymes involved in the pathogenesis
Alzheimer's disease (AD) including prime amyloid beta (Aβ) producing enzyme (β …