Respiratory risks from household air pollution in low and middle income countries

SB Gordon, NG Bruce, J Grigg, PL Hibberd… - The lancet Respiratory …, 2014 - thelancet.com
A third of the world's population uses solid fuel derived from plant material (biomass) or coal
for cooking, heating, or lighting. These fuels are smoky, often used in an open fire or simple …

T-helper-1-cell cytokines drive cancer into senescence

H Braumüller, T Wieder, E Brenner, S Aßmann, M Hahn… - Nature, 2013 - nature.com
Cancer control by adaptive immunity involves a number of defined death,,,,,,, and clearance,,
mechanisms. However, efficient inhibition of exponential cancer growth by T cells and …

Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment

C Rodriguez-Antona, A Gomez, M Karlgren, SC Sim… - Human genetics, 2010 - Springer
The cytochromes P450 (CYPs) are very efficient catalysts of foreign compound metabolism
and are responsible for the major part of metabolism of clinically important drugs. The …

Estimating and explaining the effect of education and income on head and neck cancer risk: INHANCE consortium pooled analysis of 31 case‐control studies from 27 …

DI Conway, DR Brenner, AD McMahon… - … journal of cancer, 2015 - Wiley Online Library
Low socioeconomic status has been reported to be associated with head and neck cancer
risk. However, previous studies have been too small to examine the associations by cancer …

Clinical features and prognostic factors in patients with head and neck cancer: Results from a multicentric study

E Leoncini, V Vukovic, G Cadoni, R Pastorino… - Cancer …, 2015 - Elsevier
Background The purpose of this study is to evaluate whether demographics, lifestyle habits,
clinical data and alcohol dehydrogenase polymorphisms rs1229984 and rs1573496 …

Cancer stem cells hypothesis and stem cells in head and neck cancers

G Mannelli, O Gallo - Cancer treatment reviews, 2012 - Elsevier
There is increasing evidence that the growth and spread of cancer is driven by a small
subpopulation of cancer cells, defined as cancer stem cells (CSCs). Recent data indicate …

Pro-inflammatory cytokines alter the immunopeptidome landscape by modulation of HLA-B expression

A Javitt, E Barnea, MP Kramer, H Wolf-Levy… - Frontiers in …, 2019 - frontiersin.org
Antigen presentation on HLA molecules is a major mechanism by which the immune system
monitors self and non-self-recognition. Importantly, HLA-I presentation has gained much …

Roles of HIF and 2-oxoglutarate-dependent dioxygenases in controlling gene expression in hypoxia

J Frost, M Frost, M Batie, H Jiang, S Rocha - Cancers, 2021 - mdpi.com
Simple Summary Hypoxia—reduction in oxygen availability—plays key roles in both
physiological and pathological processes. Given the importance of oxygen for cell and …

Alcohol Exposure In Utero and Child Academic Achievement

S von Hinke Kessler Scholder, GL Wehby… - The Economic …, 2014 - academic.oup.com
We examine the effect of prenatal alcohol exposure on child academic achievement. We use
a genetic variant in the maternal alcohol‐metabolism gene ADH1B to instrument for alcohol …

Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers

E Schuit, OA Panagiotou, MR Munafò… - Cochrane Database …, 2017 - cochranelibrary.com
Background Smoking cessation therapies are not effective for all smokers, and researchers
are interested in identifying those subgroups of individuals (eg based on genotype) who …