How the PhoP/PhoQ System Controls Virulence and Mg2+ Homeostasis: Lessons in Signal Transduction, Pathogenesis, Physiology, and Evolution

EA Groisman, A Duprey, J Choi - Microbiology and Molecular …, 2021 - Am Soc Microbiol
SUMMARY The PhoP/PhoQ two-component system governs virulence, Mg2+ homeostasis,
and resistance to a variety of antimicrobial agents, including acidic pH and cationic …

Salmonella Biofilm Formation, Chronic Infection, and Immunity Within the Intestine and Hepatobiliary Tract

JE Harrell, MM Hahn, SJ D'Souza… - Frontiers in cellular …, 2021 - frontiersin.org
Within the species of Salmonella enterica, there is significant diversity represented among
the numerous subspecies and serovars. Collectively, these account for microbes with …

Salmonella Virulence and Immune Escape

M Wang, IH Qazi, L Wang, G Zhou, H Han - Microorganisms, 2020 - mdpi.com
Salmonella genus represents the most common foodborne pathogens causing morbidity,
mortality, and burden of disease in all regions of the world. The introduction of antimicrobial …

Host cell targeting by enteropathogenic bacteria T3SS effectors

L Pinaud, PJ Sansonetti, A Phalipon - Trends in microbiology, 2018 - cell.com
Microbial pathogens possess a diversity of weapons that disrupt host homeostasis and
immune defenses, thus resulting in the establishment of infection. The best-characterized …

Membrane vesicles are immunogenic facsimiles of Salmonella typhimurium that potently activate dendritic cells, prime B and T cell responses, and stimulate protective …

RC Alaniz, BL Deatherage, JC Lara… - The Journal of …, 2007 - journals.aai.org
Gram-negative bacteria produce membrane vesicles (MVs) from their outer membrane
during growth, although the mechanism for MV production and the advantage that MVs …

Biogenesis of bacterial membrane vesicles

BL Deatherage, JC Lara, T Bergsbaken… - Molecular …, 2009 - Wiley Online Library
Membrane vesicle (MV) release remains undefined, despite its conservation among
replicating Gram‐negative bacteria both in vitro and in vivo. Proteins identified in Salmonella …

Salmonella‐Containing Vacuoles: Directing Traffic and Nesting to Grow

MA Bakowski, V Braun, JH Brumell - Traffic, 2008 - Wiley Online Library
Salmonella enterica serovar Typhimurium (S. typhimurium) is a gram‐negative facultative
intracellular pathogen that can infect a broad range of mammalian hosts. Following invasion …

Dynamics of growth and dissemination of Salmonella in vivo

KG Watson, DW Holden - Cellular microbiology, 2010 - Wiley Online Library
The last decade has witnessed increasing research on dissemination of bacterial pathogens
in their hosts and on the processes that underlie bacterial spread and growth during organ …

Identification of Salmonella Pathogenicity Island-2 Type III Secretion System Effectors Involved in Intramacrophage Replication of S. enterica Serovar Typhimurium …

R Figueira, KG Watson, DW Holden, S Helaine - MBio, 2013 - Am Soc Microbiol
Salmonella enterica serovars cause severe diseases in humans, such as gastroenteritis and
typhoid fever. The development of systemic disease is dependent on a type III secretion …

The Salmonella SPI2 Effector SseI Mediates Long-Term Systemic Infection by Modulating Host Cell Migration

LM McLaughlin, GR Govoni, C Gerke… - PLoS …, 2009 - journals.plos.org
Host-adapted strains of Salmonella enterica cause systemic infections and have the ability
to persist systemically for long periods of time despite the presence of a robust immune …