Rubisco function, evolution, and engineering
Carbon fixation is the process by which CO2 is converted from a gas into biomass. The
Calvin–Benson–Bassham cycle (CBB) is the dominant carbon-consuming pathway on …
Calvin–Benson–Bassham cycle (CBB) is the dominant carbon-consuming pathway on …
Macromolecular crowding, phase separation, and homeostasis in the orchestration of bacterial cellular functions
Macromolecular crowding affects the activity of proteins and functional macromolecular
complexes in all cells, including bacteria. Crowding, together with physicochemical …
complexes in all cells, including bacteria. Crowding, together with physicochemical …
The eukaryotic linear motif resource: 2022 release
M Kumar, S Michael, J Alvarado-Valverde… - Nucleic acids …, 2022 - academic.oup.com
Almost twenty years after its initial release, the Eukaryotic Linear Motif (ELM) resource
remains an invaluable source of information for the study of motif-mediated protein-protein …
remains an invaluable source of information for the study of motif-mediated protein-protein …
Modelling the pyrenoid-based CO2-concentrating mechanism provides insights into its operating principles and a roadmap for its engineering into crops
Many eukaryotic photosynthetic organisms enhance their carbon uptake by supplying
concentrated CO2 to the CO2-fixing enzyme Rubisco in an organelle called the pyrenoid …
concentrated CO2 to the CO2-fixing enzyme Rubisco in an organelle called the pyrenoid …
Identification of a carbonic anhydrase–Rubisco complex within the alpha-carboxysome
C Blikstad, EJ Dugan, TG Laughlin… - Proceedings of the …, 2023 - National Acad Sciences
Carboxysomes are proteinaceous organelles that encapsulate key enzymes of CO2 fixation—
Rubisco and carbonic anhydrase—and are the centerpiece of the bacterial CO2 …
Rubisco and carbonic anhydrase—and are the centerpiece of the bacterial CO2 …
New horizons for building pyrenoid-based CO2-concentrating mechanisms in plants to improve yields
L Adler, A Díaz-Ramos, Y Mao, KR Pukacz… - Plant …, 2022 - academic.oup.com
Many photosynthetic species have evolved CO2-concentrating mechanisms (CCMs) to
improve the efficiency of CO2 assimilation by Rubisco and reduce the negative impacts of …
improve the efficiency of CO2 assimilation by Rubisco and reduce the negative impacts of …
Deep learning improves macromolecule identification in 3D cellular cryo-electron tomograms
Cryogenic electron tomography (cryo-ET) visualizes the 3D spatial distribution of
macromolecules at nanometer resolution inside native cells. However, automated …
macromolecules at nanometer resolution inside native cells. However, automated …
A promiscuous mechanism to phase separate eukaryotic carbon fixation in the green lineage
CO2 fixation is commonly limited by inefficiency of the CO2-fixing enzyme Rubisco.
Eukaryotic algae concentrate and fix CO2 in phase-separated condensates called …
Eukaryotic algae concentrate and fix CO2 in phase-separated condensates called …
[HTML][HTML] Pyrenoids: CO2-fixing phase separated liquid organelles
J Barrett, P Girr, LCM Mackinder - … et Biophysica Acta (BBA)-Molecular Cell …, 2021 - Elsevier
Pyrenoids are non-membrane bound organelles found in chloroplasts of algae and hornwort
plants that can be seen by light-microscopy. Pyrenoids are formed by liquid-liquid phase …
plants that can be seen by light-microscopy. Pyrenoids are formed by liquid-liquid phase …
[HTML][HTML] Phase separation in biology and disease; current perspectives and open questions
In the past almost 15 years, we witnessed the birth of a new scientific field focused on the
existence, formation, biological functions, and disease associations of membraneless …
existence, formation, biological functions, and disease associations of membraneless …