Metabolomics for investigating physiological and pathophysiological processes

DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …

Cancer biomarkers and their biosensors: A comprehensive review

H Khan, MR Shah, J Barek, MI Malik - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The article starts with a brief history of discovery of cancer biomarkers followed by statistical
data on published cancer biomarkers detection strategies in the last decade to demonstrate …

Non-invasive biomarkers for early detection of breast cancer

J Li, X Guan, Z Fan, LM Ching, Y Li, X Wang, WM Cao… - Cancers, 2020 - mdpi.com
Simple Summary Early diagnosis of breast cancer greatly increases the chance of cure and
survival from the disease. The mammogram is widely used for early detection of breast …

Metabolic phenotyping in clinical and surgical environments

JK Nicholson, E Holmes, JM Kinross, AW Darzi… - Nature, 2012 - nature.com
Metabolic phenotyping involves the comprehensive analysis of biological fluids or tissue
samples. This analysis allows biochemical classification of a person's physiological or …

The human circadian metabolome

R Dallmann, AU Viola, L Tarokh… - Proceedings of the …, 2012 - National Acad Sciences
The circadian clock orchestrates many aspects of human physiology, and disruption of this
clock has been implicated in various pathologies, ranging from cancer to metabolic …

Current and emerging methods for ovarian cancer screening and diagnostics: a comprehensive review

JM Liberto, SY Chen, IM Shih, TH Wang, TL Wang… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

Understanding the role of gut microbiome–host metabolic signal disruption in health and disease

E Holmes, JV Li, T Athanasiou, H Ashrafian… - Trends in …, 2011 - cell.com
There is growing awareness of the importance of the gut microbiome in health and disease,
and recognition that the microbe to host metabolic signalling is crucial to understanding the …

Urine biomarkers in cancer detection: A systematic review of preanalytical parameters and applied methods

S Jordaens, K Zwaenepoel, W Tjalma… - … Journal of Cancer, 2023 - Wiley Online Library
The aim of this review was to explore the status of urine sampling as a liquid biopsy for
noninvasive cancer research by reviewing used preanalytical parameters and protocols. We …

Plasma free amino acid profiling of five types of cancer patients and its application for early detection

Y Miyagi, M Higashiyama, A Gochi, M Akaike… - PloS one, 2011 - journals.plos.org
Background Recently, rapid advances have been made in metabolomics-based, easy-to-
use early cancer detection methods using blood samples. Among metabolites, profiling of …

Breast cancer in the era of integrating “Omics” approaches

C Rossi, I Cicalini, MC Cufaro, A Consalvo… - Oncogenesis, 2022 - nature.com
Worldwide, breast cancer is the leading cause of cancer-related deaths in women. Breast
cancer is a heterogeneous disease characterized by different clinical outcomes in terms of …