[HTML][HTML] Research progress, challenges and perspectives on PNPLA3 and its variants in Liver Diseases
H Xiang, Z Wu, J Wang, T Wu - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
The human patatin-like phospholipase domain-containing 3 gene (PNPLA3) is highly
expressed in liver and adipose tissue and encodes a transmembrane polypeptide chain …
expressed in liver and adipose tissue and encodes a transmembrane polypeptide chain …
The roles of transmembrane 6 superfamily member 2 rs58542926 polymorphism in chronic liver disease: a meta‐analysis of 24,147 subjects
X Chen, P Zhou, L De, B Li, S Su - Molecular genetics & …, 2019 - Wiley Online Library
Background Some genetic association studies tried to investigate potential associations of
transmembrane 6 superfamily member 2 (TM6SF2) polymorphisms with chronic liver …
transmembrane 6 superfamily member 2 (TM6SF2) polymorphisms with chronic liver …
Impact of PNPLA3 I148M on alpha-1 antitrypsin deficiency-dependent liver disease progression
I Volkert, M Fromme, C Schneider, L Candels… - Hepatology, 2024 - journals.lww.com
Impact of PNPLA3 I148M on alpha-1 antitrypsin deficiency-dep... : Hepatology Impact of
PNPLA3 I148M on alpha-1 antitrypsin deficiency-dependent liver disease progression …
PNPLA3 I148M on alpha-1 antitrypsin deficiency-dependent liver disease progression …
Donor PNPLA3 and TM6SF2 variant alleles confer additive risks for graft steatosis after liver transplantation
I Míková, M Neroldová, JA Hubácek, D Dlouhá… - …, 2020 - journals.lww.com
Background. The rs58542926 polymorphism in transmembrane 6 superfamily member 2
(TM6SF2) is a genetic factor predisposing to nonalcoholic fatty liver disease. We aimed to …
(TM6SF2) is a genetic factor predisposing to nonalcoholic fatty liver disease. We aimed to …
PNPLA3 and IL 28B signature for predicting susceptibility to chronic hepatitis C infection and fibrosis progression
SS Youssef, EAER Abbas, RA Youness… - … of physiology and …, 2022 - Taylor & Francis
Background Association studies identified genetic polymorphisms as predictive risk factors
of rapid fibrosis progression in chronic hepatitis C (CHC). This study aims to assess the …
of rapid fibrosis progression in chronic hepatitis C (CHC). This study aims to assess the …
[HTML][HTML] Contribution of PNPLA3 gene polymorphisms to hepatocellular carcinoma susceptibility in the Chinese Han population
D Gong, S Li, Z Yu, K Wang, X Qiao, C Wu - BMC Medical Genomics, 2022 - Springer
Objectives The purpose of this study was to investigate the association of PNPLA3 single
nucleotide polymorphisms (SNPs)(rs738409 C> G, rs3747207 G> A, rs4823173 G> A, and …
nucleotide polymorphisms (SNPs)(rs738409 C> G, rs3747207 G> A, rs4823173 G> A, and …
[HTML][HTML] Effect of MTTP-493G/T, I128T, Q95H and Q244E polymorphisms on hepatic steatosis in patients with chronic hepatitis
TVG Prata, C Manchiero, BP Dantas… - Clinics, 2022 - Elsevier
Background Chronic hepatitis C is characterized by a progressive deterioration of liver
function and is involved in metabolic complications, such as hepatic steatosis. Objective The …
function and is involved in metabolic complications, such as hepatic steatosis. Objective The …
[HTML][HTML] TGF-Β1 & PNPLA3 genetic variants and the risk of hepatic fibrosis and HCC in Egyptian patients with HCV-related liver cirrhosis
AM Nomair, LS Kandil, HM Nomeir… - Asian Pacific Journal of …, 2021 - ncbi.nlm.nih.gov
Objective: The clinical outcomes of hepatitis C virus (HCV) infection and its sequelae
including liver cirrhosis and hepatocellular carcinoma (HCC) are greatly affected by host …
including liver cirrhosis and hepatocellular carcinoma (HCC) are greatly affected by host …
A study of genetic variants, genetic risk score and DNA methylation of PNPLA3 and TM6SF2 in alcohol liver cirrhosis
B Shankarappa, J Mahadevan, P Murthy… - Indian Journal of …, 2023 - Springer
Background Genetic and epigenetic factors are associated with the development of alcohol-
associated liver disease (AALD). The single nucleotide polymorphisms (SNPs), rs738409 in …
associated liver disease (AALD). The single nucleotide polymorphisms (SNPs), rs738409 in …
[PDF][PDF] Association between PNPLA3 [G]/I148M variant, steatosis and fibrosis stage in hepatitis C virus-genetic matters
D Crisan, M Grigorescu, N Crisan, R Craciun… - J Physiol …, 2019 - academia.edu
There is an established correlation between the PNPLA3 rs738409 C> G single nucleotide
polymorphism (SNP) and hepatic steatosis and fibrosis in hepatitis C virus (HCV) infected …
polymorphism (SNP) and hepatic steatosis and fibrosis in hepatitis C virus (HCV) infected …