Oxadiazole: A highly versatile scaffold in drug discovery

N Desai, J Monapara, A Jethawa… - Archiv der …, 2022 - Wiley Online Library
As a pharmacologically important heterocycle, oxadiazole paved the way to combat the
problem associated with the confluence of many commercially available drugs with different …

[HTML][HTML] Therapeutic potential of oxadiazole or furadiazole containing compounds

A Siwach, PK Verma - BMC chemistry, 2020 - Springer
As we know that, Oxadiazole or furadi azole ring containing derivatives are an important
class of heterocyclic compounds. A heterocyclic five-membered ring that possesses two …

Updates on synthesis and biological activities of 1, 3, 4-oxadiazole: A review

Salahuddin, A Mazumder, MS Yar… - Synthetic …, 2017 - Taylor & Francis
The new era of heterocyclic moieties which are developed in the decades plays a very
important role in the treatment of various diseases. Among them are 1, 3, 4-oxadiazoles, a …

Synthesis, biological evaluation and docking studies of 1, 3, 4-oxadiazole fused benzothiazole derivatives for anticancer drugs

M Subramanyam, R Sreenivasulu… - Letters in Drug …, 2018 - ingentaconnect.com
Background: Hetero atom containing compounds are well studied class of organic
compounds exhibits variety of properties and applications. Design and synthesis of new …

New structural classes of antituberculosis agents

V Kumar, S Patel, R Jain - Medicinal Research Reviews, 2018 - Wiley Online Library
Tuberculosis (TB), one of the deadliest diseases is shattering the health and socioeconomic
status of the society. The emergence of multidrug resistant (MDR) and extremely drug …

Synthesis, characterization, free-radical scavenging capacity and antioxidant activity of novel series of hydrazone, 1, 3, 4-oxadiazole and 1, 2, 4-triazole derived from 3 …

K Karrouchi, S Fettach, S Radi, J Taoufik… - Letters in Drug …, 2019 - ingentaconnect.com
Background: Pyrazole is an important class of heterocyclic compound, has been shown to
exhibit diverse biological and pharmacological activities such as anti-inflammatory, anti …

[HTML][HTML] Free radical scavenging mechanism of 1, 3, 4-oxadiazole derivatives: thermodynamics of O–H and N–H bond cleavage

IO Alisi, A Uzairu, SE Abechi - Heliyon, 2020 - cell.com
The thermodynamics of free radical scavenge of 1, 3, 4-oxadiazole derivatives towards
oxygen-centred free radicals were investigated by the density functional theory (DFT) …

1, 3‐Oxazole‐isoniazid hybrids: Synthesis, antitubercular activity, and their docking studies

SR Shah, KD Katariya - Journal of Heterocyclic Chemistry, 2020 - Wiley Online Library
A series of novel N′‐([2‐aryl‐5‐methyl‐1, 3‐oxazole‐4‐yl] methylene) isonicotino/nicotino
hydrazides 10a‐l were prepared by the condensation reaction of 2‐aryl‐5‐methyl‐1, 3 …

Design, synthesis and characterization of novel amine derivatives of 5-[5-(chloromethyl)-1, 3, 4-oxadiazol-2-yl]-2-(4-fluorophenyl)-pyridine as a new class of …

A Vinayak, M Sudha, KS Lalita - Dhaka University Journal of …, 2017 - banglajol.info
Design, Synthesis and Characterization of Novel Amine Derivatives of 5-[5-(Chloromethyl)-1, 3,
4-Oxadiazol-2-yl]- 2-(4-Fluorophe Page 1 Design, Synthesis and Characterization of Novel …

[PDF][PDF] Biological aspects of 1, 3, 4-oxadiazole derivatives

S Kavitha, S Gnanavel, K Kannan - Asian Journal of Pharmaceutical and …, 2014 - core.ac.uk
Heterocyclic compounds analog have attracted wide attention due to their useful biological
properties. Among them, 1, 3, 4-oxadiazoles have exhibited a wide range of biological …