Pathogenesis and management of abdominal aortic aneurysm

J Golledge, S Thanigaimani, JT Powell… - European Heart …, 2023 - academic.oup.com
Abdominal aortic aneurysm (AAA) causes∼ 170 000 deaths annually worldwide. Most
guidelines recommend asymptomatic small AAAs (30 to< 50 mm in women; 30 to< 55 mm in …

Abdominal aortic aneurysm: novel mechanisms and therapies

FM Davis, DL Rateri, A Daugherty - Current opinion in cardiology, 2015 - journals.lww.com
Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion in
Cardiology Abdominal aortic aneurysm: novel mechanisms and therapies : Current Opinion …

[HTML][HTML] The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm

EL Chaikof, RL Dalman, MK Eskandari… - Journal of vascular …, 2018 - Elsevier
Background Decision-making related to the care of patients with an abdominal aortic
aneurysm (AAA) is complex. Aneurysms present with varying risks of rupture, and patient …

Gut microbiota–derived trimethylamine N-oxide contributes to abdominal aortic aneurysm through inflammatory and apoptotic mechanisms

TW Benson, KA Conrad, XS Li, Z Wang, RN Helsley… - Circulation, 2023 - Am Heart Assoc
Background: Large-scale human and mechanistic mouse studies indicate a strong
relationship between the microbiome-dependent metabolite trimethylamine N-oxide (TMAO) …

Targeting macrophage TFEB-14-3-3 epsilon Interface by naringenin inhibits abdominal aortic aneurysm

Y Jia, L Zhang, Z Liu, C Mao, Z Ma, W Li, F Yu, Y Wang… - Cell Discovery, 2022 - nature.com
Abdominal aortic aneurysm (AAA) is a lethal cardiovascular disease, and there is no proven
drug treatment for this condition. In this study, by using the Connectivity Map (CMap) …

Projection of global burden and risk factors for aortic aneurysm–timely warning for greater emphasis on managing blood pressure

X Huang, Z Wang, Z Shen, F Lei, YM Liu… - Annals of …, 2022 - Taylor & Francis
Rationale Aortic aneurysm (AA) is a serious condition that largely increases the risk of aortic
dissection and sudden death. Exploring the global burden of disease and changes in risk …

Pharmacological therapy of abdominal aortic aneurysm: an update

Y Wang, Z Liu, J Ren, M Xiang - Current vascular …, 2018 - ingentaconnect.com
Background: Abdominal aortic aneurysm (AAA), a progressive segmental abdominal aortic
dilation, is associated with high mortality. AAA is characterized by inflammation, smooth …

Association of long-term use of antihypertensive medications with late outcomes among patients with aortic dissection

SW Chen, YH Chan, CP Lin, VCC Wu… - JAMA Network …, 2021 - jamanetwork.com
Importance The associations between long-term treatment of aortic dissection with various
medications and late patient outcomes are poorly understood. Objective To compare late …

HIV infection is associated with thoracic and abdominal aortic aneurysms: a prospective matched cohort study

J Høgh, MHC Pham, AD Knudsen… - European Heart …, 2021 - academic.oup.com
Aims Little is known about the prevalence of aortic aneurysms among people living with HIV
(PLWH). We investigated whether HIV status is independently associated with having aortic …

[HTML][HTML] Endothelium as a potential target for treatment of abdominal aortic aneurysm

J Sun, H Deng, Z Zhou, X Xiong, L Gao - Oxidative Medicine and …, 2018 - hindawi.com
Abdominal aortic aneurysm (AAA) was previously ascribed to weaken defective medial
arterial/adventitial layers, for example, smooth muscle/fibroblast cells. Therefore, besides …