Studies of families and twins show the importance of genetic factors affecting susceptibility to
bipolar disorder and suggest substantial genetic and phenotypic complexity. Robust and …

Major efforts have been directed at family-based association and case–control studies to
identify the involvement of candidate genes in the major disorders of mental health. What …

Background To study differences in oxidative stress markers and antioxidants among
patients with bipolar depression (BPD) and unipolar depression (UPD). Methods Data …

Bipolar disorder (BD) is a complex disorder with a range of presentations. BD is defined by
the presentation of symptoms of mania or depression, with classification dependent on …

After more than 10 years of accumulated efforts, genome-wide association studies (GWAS)
have led to many findings, most of which have been deposited into the GWAS Catalog …

Background Genetic risk is thought to drive clinical variation on a spectrum of schizophrenia-
like traits, but the underlying changes in brain structure that mechanistically link genomic …

Aggressive individuals have higher rates of mental illness compared to non-aggressive
individuals. Multiple factors, including psychosocial, genetic, and neurobiological …

Over the last two decades, it has become increasingly evident that control of aggressive
behavior is modulated by the individual genetic profile as well. Several candidate genes …

Objective Previous studies have suggested an immunological dysfunction in mood
disorders, but rarely have investigated the temporal association between allergic diseases …

Background There is an emerging interest in the use of cellular models to study psychiatric
disorders. We have systematically reviewed the application of cellular models to understand …