Owing to advances in genome sequencing, genome stability has become one of the most
scrutinized cellular traits across the Tree of Life. Despite its centrality to all things biological …

The germline mutation rate determines the pace of genome evolution and is an evolving
parameter itself. However, little is known about what determines its evolution, as most …

Germline mutations are the source of all heritable variation. In the past few years, whole
genome sequencing has allowed direct and comprehensive surveys of mutation patterns in …

The textbook view that most germline mutations in mammals arise from replication errors is
indirectly supported by the fact that there are both more mutations and more cell divisions in …

The human mutation rate per generation estimated from trio sequencing has revealed an
almost linear relationship with the age of the father and the age of the mother, with fathers …

In the past decade, several studies have estimated the human per-generation germline
mutation rate using large pedigrees. More recently, estimates for various nonhuman species …

Global biodiversity is under accelerating threats, and species are succumbing to extinction
before being described. Madagascar's biota represents an extreme example of this …

Mutation is the ultimate source of all genetic variation, and over the last 10 years the ready
availability of whole-genome sequencing has permitted direct estimation of mutation rate for …

We sequenced and assembled using multiple long-read sequencing technologies the
genomes of chimpanzee, bonobo, gorilla, orangutan, gibbon, macaque, owl monkey, and …

Mutation is the source of genetic variation and the fundament of evolution. Temperature has
long been suggested to have a direct impact on realized spontaneous mutation rates. If …