[HTML][HTML] Link between microbiota and hypertension: Focus on LPS/TLR4 pathway in endothelial dysfunction and vascular inflammation, and therapeutic implication of …
High blood pressure (BP) presents a significant public health challenge. Recent findings
suggest that altered microbiota can exert a hypertensive effect on the host. One of the …
suggest that altered microbiota can exert a hypertensive effect on the host. One of the …
Endothelial-to-mesenchymal transition: cytokine-mediated pathways that determine endothelial fibrosis under inflammatory conditions
During the last decade, the endothelial-to-mesenchymal transition (EndMT) process has
attracted considerable attention due to associations with the onset of certain diseases, such …
attracted considerable attention due to associations with the onset of certain diseases, such …
ROS signaling in the pathogenesis of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS)
M Kellner, S Noonepalle, Q Lu, A Srivastava… - … redox signaling in …, 2017 - Springer
The generation of reactive oxygen species (ROS) plays an important role for the
maintenance of cellular processes and functions in the body. However, the excessive …
maintenance of cellular processes and functions in the body. However, the excessive …
[HTML][HTML] TRPM7 channel inhibition attenuates rheumatoid arthritis articular chondrocyte ferroptosis by suppression of the PKCα-NOX4 axis
R Zhou, Y Chen, S Li, X Wei, W Hu, J Ding, W Fu… - Redox biology, 2022 - Elsevier
A role for ferroptosis in articular cartilage destruction associated with rheumatoid arthritis
(RA) has not been identified. We previously reported transient receptor potential melastatin …
(RA) has not been identified. We previously reported transient receptor potential melastatin …
Visfatin/eNampt induces endothelial dysfunction in vivo: a role for Toll-Like Receptor 4 and NLRP3 inflammasome
T Romacho, I Valencia, M Ramos-González… - Scientific reports, 2020 - nature.com
Abstract Visfatin/extracellular-nicotinamide-phosphoribosyltranferase-(eNampt) is a
multifaceted adipokine enhanced in type-2-diabetes and obesity. Visfatin/eNampt cause in …
multifaceted adipokine enhanced in type-2-diabetes and obesity. Visfatin/eNampt cause in …
TRPM channels in human diseases
The transient receptor potential melastatin (TRPM) subfamily belongs to the TRP cation
channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been …
channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been …
Lipopolysaccharides from Porphyromonas endodontalis and Porphyromonas gingivalis promote angiogenesis via Toll‐like‐receptors 2 and 4 pathways in vitro
A Fernández, D Herrera, A Hoare… - International …, 2023 - Wiley Online Library
Aim Angiogenesis contributes to the development of apical periodontitis, periodontitis, and
other oral pathologies; however, it remains unclear how this process is triggered. The aim …
other oral pathologies; however, it remains unclear how this process is triggered. The aim …
Small extracellular vesicles secreted from human amniotic fluid mesenchymal stromal cells possess cardioprotective and promigratory potential
Mesenchymal stromal cells (MSCs) exhibit antiapoptotic and proangiogenic functions in
models of myocardial infarction which may be mediated by secreted small extracellular …
models of myocardial infarction which may be mediated by secreted small extracellular …
Different concentrations of lipopolysaccharide regulate barrier function through the PI3K/Akt signalling pathway in human pulmonary microvascular endothelial cells
X Zheng, W Zhang, X Hu - Scientific reports, 2018 - nature.com
Lipopolysaccharide (LPS) can lead to vascular endothelial barrier dysfunction, which often
results in acute lung injury and acute respiratory distress syndrome. However, the effects of …
results in acute lung injury and acute respiratory distress syndrome. However, the effects of …
LPS promotes the progression of sepsis by activation of lncRNA HULC/miR-204-5p/TRPM7 network in HUVECs
X Chen, D Song - Bioscience Reports, 2020 - portlandpress.com
Sepsis is a systemic inflammatory response syndrome caused by infection.
Lipopolysaccharide (LPS) has been reported to induce inflammatory responses, and long …
Lipopolysaccharide (LPS) has been reported to induce inflammatory responses, and long …