The LIM kinases 1 and 2 (LIMK1 and LIMK2) are dual specificity (serine/threonine and
tyrosine) kinases. Although they show significant structural similarity, LIMK1 and LIMK2 …

Differentiated sex chromosomes are believed to be evolutionarily stable, while poorly
differentiated sex chromosomes are considered to be prone to turnovers. With around 1700 …

Xiang pig (XP) is one of the best-known indigenous pig breeds in China, which is
characterized by its small body size, strong disease resistance, high adaptability, favorite …

Prenatal maternal stress has a negative impact on child health but the mechanisms through
which maternal stress affects child health are unclear. Epigenetic variation, such as DNA …

Understanding the genetic basis of idiopathic male infertility has long been the focus of
many researchers. Numerous recent studies have attempted to identify relevant single …

Infertility is a prevalent health issue, affecting∼ 15% of couples of childbearing age. Nearly
one-half of idiopathic infertility cases are thought to have a genetic basis, but the underlying …

Purpose To identify clinically significant genomic copy number (CNV) and single nucleotide
variants (SNV) in males with unexplained spermatogenic failure (SPGF). Materials and …

SET binding factor 1 (SBF1) mutation causes Charcot-Marie-Tooth disease type 4B3 | Neurology
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The two members of the LIM domain kinase family (LIMK1 and LIMK2) represent crucial
keys in the signaling pathways that modulate the structure and activity of actin cytoskeleton …

Over the past few decades with the rapid advances in embryo and embryonic stem cell
manipulation techniques, transgenic mouse models have emerged as a powerful tool for the …