As our understanding of the cell interior has grown, we have come to appreciate that most
cellular operations are localized, that is, they occur at discrete and identifiable locations or …

In the past two decades, significant progress has been made in our understanding of mRNA
localization and translation at distal sites in axons and dendrites. The existing literature …

The branching of axons is a fundamental aspect of nervous system development and
neuroplasticity. We report that branching of sensory axons in the presence of nerve growth …

TDP-43 is a well known RNA binding protein involved in the pathogenesis of Amyotrophic
Lateral Sclerosis (ALS) and Frontotemporal Lobar Dementia (FTLD). In physiological …

The molecular function and fate of mRNAs are controlled by RNA-binding proteins (RBPs).
Identification of the interacting proteome of a specific mRNA in vivo remains very …

Ribosome biogenesis is the most demanding energetic and metabolic expenditure of the
cell. The nucleolus, a nuclear compartment, coordinates rRNA transcription, maturation, and …

Abstract Receptor for Activated C-Kinase 1 (RACK1) belongs to the WD40 family of proteins,
known to act as scaffolding proteins in interaction networks. Accordingly, RACK1 is found to …

Ribosomes have been long considered as executors of the translational program. The fact
that ribosomes can control the translation of specific mRNAs or entire cellular programs is …

Gene expression is tightly regulated by RNA-binding proteins (RBPs) to facilitate cell
survival, differentiation, and migration. Previous reports have shown the importance of the …

Gene expression is shaped by translational control. The modalities and the extent by which
translation factors modify gene expression have revealed therapeutic scenarios. For …