Cardiotoxicity of anthracyclines

D Cardinale, F Iacopo, CM Cipolla - Frontiers in cardiovascular …, 2020 - frontiersin.org
Cardiotoxicity is a feared side effect that may limit the clinical use of anthracyclines. It may
indeed affect the quality of life and survival of patients with cancer, regardless of oncological …

The Role of Cardioprotection in Cancer Therapy Cardiotoxicity: JACC: CardioOncology State-of-the-Art Review

T Omland, SL Heck, G Gulati - Cardio Oncology, 2022 - jacc.org
Cardiotoxicity is a relatively frequent and potentially serious side effect of traditional and
targeted cancer therapies. Both general measures and specific pharmacologic …

2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic …

AR Lyon, T Lopez-Fernandez, LS Couch… - European Heart …, 2022 - academic.oup.com
ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …

Cardiotoxicity of anticancer drugs: Molecular mechanisms and strategies for cardioprotection

MB Morelli, C Bongiovanni, S Da Pra… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy and targeted therapies have significantly improved the prognosis of
oncology patients. However, these antineoplastic treatments may also induce adverse …

[HTML][HTML] Anthracycline-induced cardiotoxicity—are we about to clear this hurdle?

WCM Dempke, R Zielinski, C Winkler… - European Journal of …, 2023 - Elsevier
Anthracyclines have contributed significantly to remarkable improvements in overall survival
and are regarded as the most effective cytostatic drug for cancer treatment in various …

The cancer patient and cardiology

JL Zamorano, C Gottfridsson… - European journal of …, 2020 - Wiley Online Library
Advances in cancer treatments have improved clinical outcomes, leading to an increasing
population of cancer survivors. However, this success is associated with high rates of short …

Anthracycline toxicity: light at the end of the tunnel?

RB Cejas, K Petrykey, Y Sapkota… - Annual Review of …, 2024 - annualreviews.org
Anthracycline-induced cardiotoxicity (AIC) is a serious and common side effect of
anthracycline therapy. Identification of genes and genetic variants associated with AIC risk …

Anthracycline-induced cardiotoxicity: mechanisms of action, incidence, risk factors, prevention, and treatment

Y Saleh, O Abdelkarim, K Herzallah, GS Abela - Heart failure reviews, 2021 - Springer
Anthracycline is a mainstay in treatment of many cancers including lymphoma and breast
cancer among many others. However, anthracycline treatment can be cardiotoxic. Although …

Statins to prevent early cardiac dysfunction in cancer patients at increased cardiotoxicity risk receiving anthracyclines

P Thavendiranathan, C Houbois… - European Heart …, 2023 - academic.oup.com
Background and aims Anthracyclines can cause cancer therapy-related cardiac dysfunction
(CTRCD). We aimed to assess whether statins prevent decline in left ventricular ejection …

Doxorubicin-induced acute cardiotoxicity is associated with increased oxidative stress, autophagy, and inflammation in a murine model

PL Dulf, M Mocan, CA Coadă, DV Dulf… - Naunyn-Schmiedeberg's …, 2023 - Springer
Drug-induced cardiotoxicity is a life-threatening side effect of doxorubicin (DOX) treatment
that impacts patient prognosis and survival. In the majority of cases, the acute clinical form …