The genetically encoded fluorescent sensors convert chemical and physical signals into
light. They are powerful tools for the visualisation of physiological processes in living cells …

Modern agriculture relies on mineral fertilization. Unlike other major macronutrients,
potassium (K+) is not incorporated into organic matter but remains as soluble ion in the cell …

Fluorescence resonance energy transfer (FRET)-based biosensors are effective analytical
tools extensively used in fields of biomedicine, pharmacology, toxicology, and food …

Cell surface potassium ion (K+) channels regulate nutrient transport, cell migration and
intercellular communication by controlling K+ permeability and are thought to be active only …

Highly charged intrinsically disordered proteins are essential regulators of chromatin
structure and transcriptional activity. Here we identify a surprising mechanism of molecular …

Fluorescent biosensors are powerful analytical tools that have been widely employed in a
range of in vitro and in vivo biomedical applications. However, traditional fluorophores …

Extracellular potassium concentration affects the membrane potential of neurons, and, thus,
neuronal activity. Indeed, alterations of potassium levels can be related to neurological …

Potassium ion (K+) homeostasis and dynamics play critical roles in biological activities. Here
we describe three genetically encoded K+ indicators. KIRIN1 (potassium (K) i on r atiometric …

Nucleic acids (DNA and RNA) dynamically fold and unfold to exert their functions in cells.
These folding and unfolding behaviours are also the basis for various technical applications …

The with no lysine (K)(WNK) kinases are an evolutionarily ancient group of kinases with
atypical placement of the catalytic lysine and diverse physiological roles. Recent studies …