Dendrimers in vaccine delivery: Recent progress and advances
Dendrimers are well-defined, highly branched, multivalent and monodisperse molecules
which host a range of attractive, yet functional, chemical and biological characteristics. A …
which host a range of attractive, yet functional, chemical and biological characteristics. A …
[HTML][HTML] Therapeutic potential of polypeptide-based conjugates: rational design and analytical tools that can boost clinical translation
T Melnyk, S Đorđević, I Conejos-Sanchez… - Advanced drug delivery …, 2020 - Elsevier
The clinical success of polypeptides as polymeric drugs, covered by the umbrella term
“polymer therapeutics,” combined with related scientific and technological breakthroughs …
“polymer therapeutics,” combined with related scientific and technological breakthroughs …
Functionalized branched polymers: promising immunomodulatory tools for the treatment of cancer and immune disorders
Well-defined synthetic branched nanostructures form an emerging subclass of
macromolecular structures whose 3D structure and multivalency offer unique opportunities …
macromolecular structures whose 3D structure and multivalency offer unique opportunities …
Peptide Dendrimer-Based Antibacterial Agents: Synthesis and Applications
Pathogenic bacteria cause the deaths of millions of people every year. With the
development of antibiotics, hundreds and thousands of people's lives have been saved …
development of antibiotics, hundreds and thousands of people's lives have been saved …
[HTML][HTML] Topological aspects of the design of nanocarriers for therapeutic peptides and proteins
N Knauer, E Pashkina, E Apartsin - Pharmaceutics, 2019 - mdpi.com
Supramolecular chemistry holds great potential for the design of versatile and safe carriers
for therapeutic proteins and peptides. Nanocarriers can be designed to meet specific criteria …
for therapeutic proteins and peptides. Nanocarriers can be designed to meet specific criteria …
Nanotechnology approaches to improving cancer immunotherapy
Cancer immunotherapy is a powerful, growing treatment approach to cancer that can be
combined with chemotherapy, radiotherapy, and oncosurgery. Modulating the immune …
combined with chemotherapy, radiotherapy, and oncosurgery. Modulating the immune …
Effect of the lipid composition and cholesterol on the membrane selectivity of low generations PAMAM dendrimers: A molecular dynamics simulation study
Among different nanomaterials, dendrimers stand out because of their inherent broad range
of activity against viruses, bacteria, and cancer cells. Herein, a total of 15 molecular systems …
of activity against viruses, bacteria, and cancer cells. Herein, a total of 15 molecular systems …
Computer simulation of the structural properties of fatty-acid modified PAMAM dendrimers at pH 5 and 7
C Tu, W Mou, ZL Shen - Journal of Molecular Graphics and Modelling, 2023 - Elsevier
In this work, we performed coarse-grained molecular dynamics (CGMD) simulations of G3,
G4, and G5 polyamidoamine (PAMAM) dendrimers grafting with fatty acid (FTA) chains. The …
G4, and G5 polyamidoamine (PAMAM) dendrimers grafting with fatty acid (FTA) chains. The …
An update on the use of molecular modeling in dendrimers design for biomedical applications: are we using its full potential?
M Zloh, TS Barata - Expert Opinion on Drug Discovery, 2020 - Taylor & Francis
Introduction Dendrimers are well-defined hyperbranched polymers built from a variety of
different monomers and with tuneable properties that make them suitable for different …
different monomers and with tuneable properties that make them suitable for different …