After its publication in 1999 as a DNA-binding and SMAD-binding transcription factor (TF)
that co-determines cell fate in amphibian embryos, ZEB2 was from 2003 studied by …

During development of the vertebrate sensory system, many important components like the
sense organs and cranial sensory ganglia arise within the head and neck. Two progenitor …

Touch concerns a fundamental component of sociality. In this review, we examine the
hypothesis that somatomotor development constitutes a crucial psychophysiological …

Sensorineural hearing loss is the most prevalent sensory deficit in humans. Most cases of
hearing loss are due to the degeneration of key structures of the sensory pathway in the …

Stem cell therapy is used to restore neurological function in stroke patients. We have
previously reported that ischemia-induced multipotent stem cells (iSCs), which are likely …

The Foxi3 transcription factor, expressed in the neural plate border at the end of gastrulation,
is necessary for the formation of posterior placodes and is thus important for ectodermal …

Early patterning of neural crest cells (NCCs) in the craniofacial primordium is important for
subsequent development of proper craniofacial structures. However, because of the …

The most anterior structure of the ascidian larva is made of three palps with sensory and
adhesive functions essential for metamorphosis. They derive from the anterior neural border …

Pax3/7 factors play numerous roles in the development of the dorsal nervous system of
vertebrates. From specifying neural crest at the neural plate borders, to regulating neural …

Neural crest cells exemplify cellular diversification from a multipotent progenitor population.
However, the full sequence of early molecular choices orchestrating the emergence of …