Phytochemicals gained considerable interest during the past years as source to develop
new treatment options for chemoprevention and cancer therapy. Motivated by the fact that a …

Multidrug resistance is a major factor causing the failure of cancer chemotherapy. Efflux
pumps of the ATP-binding cassette (ABC) transporter family expel a large array of diverse …

Background Apigenin is one of the most abundant dietary flavonoids that possesses multiple
bio-functions. Purpose This study was designed to determine the influence of apigenin on …

The improvement of cancer chemotherapy remains a major challenge, and thus new drugs
are urgently required to develop new treatment regimes. Curcumin, a polyphenolic …

Background The discovery of novel phytochemicals represents a reasonable approach to
fight malignancies, especially those which are resistant to standard chemotherapy. Purpose …

Resistance is the major cause of treatment failure and disease progression in non-small cell
lung cancer (NSCLC). There is evidence that hypoxia is a key microenvironmental stress …

In this chapter, the traditional use, the phytochemical composition, and the pharmacological
activities of African medicinal plants displaying antibacterial effects were reported. We have …

Overcoming multidrug resistance (MDR) represents a major obstacle in cancer
chemotherapy. Cardiac glycosides (CGs) are efficient in the treatment of heart failure and …

This study was aimed to investigate the cytotoxic potential of a natural compound, progenin
III on a broad range of cancer cell lines, including various sensitive and drug-resistant …

Background Recalcitrant cancers appear as a major obstacle to chemotherapy, prompting
scientists to intensify the search for novel drugs to tackle the cell lines expressing multi-drug …