The protein corona and its effects on nanoparticle-based drug delivery systems

H Li, Y Wang, Q Tang, D Yin, C Tang, E He, L Zou… - Acta biomaterialia, 2021 - Elsevier
In most cases, once nanoparticles (NPs) enter the blood, their surface is covered by
biological molecules, especially proteins, forming a so-called protein corona (PC). As a …

The interaction between nanoparticles-protein corona complex and cells and its toxic effect on cells

N Liu, M Tang, J Ding - Chemosphere, 2020 - Elsevier
Once nanoparticles (NPs) contact with the biological fluids, the proteins immediately adsorb
onto their surface, forming a layer called protein corona (PC), which bestows the biological …

The influence of nanoparticle shape on protein corona formation

R Madathiparambil Visalakshan, LE González García… - Small, 2020 - Wiley Online Library
Nanoparticles have become an important utility in many areas of medical treatment such as
targeted drug and treatment delivery as well as imaging and diagnostics. These advances …

Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics

P Dogra, NL Adolphi, Z Wang, YS Lin, KS Butler… - Nature …, 2018 - nature.com
The progress of nanoparticle (NP)-based drug delivery has been hindered by an inability to
establish structure-activity relationships in vivo. Here, using stable, monosized, radiolabeled …

Protein corona, influence on drug delivery system and its improvement strategy: A review

F Guo, S Luo, L Wang, M Wang, F Wu, Y Wang… - International journal of …, 2024 - Elsevier
Nano drug delivery systems offer several benefits, including enhancing drug solubility,
regulating drug release, prolonging drug circulation time, and minimized toxicity and side …

Re‐evaluation of silicon dioxide (E 551) as a food additive

EFSA Panel on Food Additives and Nutrient … - Efsa …, 2018 - Wiley Online Library
Abstract The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)
provides a scientific opinion re‐evaluating the safety of silicon dioxide (E 551) when used as …

Cytotoxicity-related bioeffects induced by nanoparticles: The role of surface chemistry

H Sun, C Jiang, L Wu, X Bai, S Zhai - Frontiers in Bioengineering and …, 2019 - frontiersin.org
Nanoparticles (NPs) are widely used in a variety of fields, including those related to
consumer products, architecture, energy, and biomedicine. Once they enter the human …

Pristine and artificially-aged polystyrene microplastic particles differ in regard to cellular response

M Völkl, V Jérôme, A Weig, J Jasinski, N Meides… - Journal of Hazardous …, 2022 - Elsevier
Microplastic particles (MP), arising from the gradual decomposition of plastics in the
environment, have been identified as a global problem. Most investigations of MP …

Nanoparticles surface chemistry influence on protein corona composition and inflammatory responses

LE González-García, MN MacGregor, RM Visalakshan… - Nanomaterials, 2022 - mdpi.com
Nanoparticles are widely used for biomedical applications such as vaccine, drug delivery,
diagnostics, and therapeutics. This study aims to reveal the influence of nanoparticle surface …

Noxic effects of polystyrene microparticles on murine macrophages and epithelial cells

J Rudolph, M Völkl, V Jérôme, T Scheibel, R Freitag - Scientific reports, 2021 - nature.com
Microplastic (MP) contamination has been identified as an ecological problem with an
increasing impact on everyday life. Yet, possible effects of MP at the cellular level are still …