[HTML][HTML] MicroRNAs as important regulators of exercise adaptation

GJJ Silva, A Bye, H El Azzouzi, U Wisløff - Progress in cardiovascular …, 2017 - Elsevier
A significant body of evidence supports the protective role of exercise training (ET) in
cardiovascular diseases, skeletal muscle dystrophies, several types of cancer, Alzheimer …

[HTML][HTML] State of knowledge on molecular adaptations to exercise in humans: historical perspectives and future directions

KM Lavin, PM Coen, LC Baptista, MB Bell… - Comprehensive …, 2022 - ncbi.nlm.nih.gov
For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

Circulatory exosomal miRNA following intense exercise is unrelated to muscle and plasma miRNA abundances

RF D'Souza, JST Woodhead, N Zeng… - American Journal …, 2018 - journals.physiology.org
MicroRNAs (miRNAs) regulate gene expression via transcript degradation and translational
inhibition, and they may also function as long distance signaling molecules. Circulatory …

[HTML][HTML] Non-coding RNAs in exercise immunology: A systematic review

M Kotewitsch, M Heimer, B Schmitz… - Journal of Sport and Health …, 2024 - Elsevier
Regular physical exercise has been recognized as a potent modulator of immune function,
with its effects including enhanced immune surveillance, reduced inflammation, and …

Physical exercise modulates miR-21-5p, miR-129-5p, miR-378-5p, and miR-188-5p expression in progenitor cells promoting osteogenesis

MT Valenti, M Deiana, S Cheri, M Dotta, F Zamboni… - Cells, 2019 - mdpi.com
Physical exercise is known to promote beneficial effects on overall health, counteracting
risks related to degenerative diseases. MicroRNAs (miRNAs), short non-coding RNAs …

Targets identified from exercised heart: killing multiple birds with one stone

H Wang, Y Xie, L Guan, K Elkin, J Xiao - npj Regenerative Medicine, 2021 - nature.com
Cardiovascular diseases (CVDs) are a major cause of mortality worldwide, which are mainly
driven by factors such as aging, sedentary lifestyle, and excess alcohol use. Exercise targets …

Specific circulating microRNAs display dose-dependent responses to variable intensity and duration of endurance exercise

AE Ramos, C Lo, LE Estephan, YY Tai… - American Journal …, 2018 - journals.physiology.org
Circulating microRNAs (c-miRNAs), plasma-based noncoding RNAs that control
posttranscriptional gene expression, mediate processes that underlie phenotypical plasticity …

The effects of moderate and high-intensity exercise on circulating markers of endothelial integrity and activation in young, healthy men

RM Sapp, WS Evans, LE Eagan… - Journal of Applied …, 2019 - journals.physiology.org
Endothelial function typically exhibits a hormetic response to exercise. It is unknown whether
endothelial damage occurs in response to acute exercise and could be a contributing …

Epigenetics in the primary and secondary prevention of cardiovascular disease: influence of exercise and nutrition

AB Gevaert, N Wood, JRA Boen… - European journal of …, 2022 - academic.oup.com
Increasing evidence links changes in epigenetic systems, such as DNA methylation, histone
modification, and non-coding RNA expression, to the occurrence of cardiovascular disease …

MicroRNAs in obesity-associated disorders: the role of exercise training

A Silveira, J Gomes, F Roque, T Fernandes… - Obesity facts, 2022 - karger.com
Obesity is a worldwide epidemic affecting over 13% of the adult population and is defined by
an excess of body fat that predisposes comorbidities. It is considered a multifactorial disease …