The potential role of miRNAs in the pathogenesis of gallbladder cancer-A focus on signaling pathways interplay

AS Doghish, HM Midan, AMM Elbadry… - … -Research and Practice, 2023 - Elsevier
Abstract microRNAs (also known as miRNAs or miRs) are a class of small non-coding RNAs
that play a critical role in post-transcriptional gene regulation as negative gene regulators by …

LncRNA-miRNA interaction is involved in colorectal cancer pathogenesis by modulating diverse signaling pathways

SH Alshahrani, ZSM Al-Hadeithi, SG Almalki… - … -Research and Practice, 2023 - Elsevier
LncRNAs function as molecular sponges for miRNAs to control their availability for targeting
mRNA molecules. This procedure indirectly regulates the expression of cancer-related …

[HTML][HTML] Inhibition of tumor progression and M2 microglial polarization by extracellular vesicle-mediated microRNA-124 in a 3D microfluidic glioblastoma …

S Hong, JY You, K Paek, J Park, SJ Kang, EH Han… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Glioblastoma (GBM) is one of the most aggressive types of brain cancer. GBM
progression is closely associated with microglia activation; therefore, understanding the …

MicroRNA‐124‐3p suppresses PD‐L1 expression and inhibits tumorigenesis of colorectal cancer cells via modulating STAT3 signaling

E Roshani Asl, Y Rasmi… - Journal of cellular …, 2021 - Wiley Online Library
Programmed death ligand 1 (PD‐L1) plays a significant role in colorectal tumorigenesis
through induction of regulatory T cells (Tregs) and suppression of antitumor immunity …

Function of microRNA-124 in the Pathogenesis of Cancer

Y Liu, Y Yang, X Wang, S Yin… - International …, 2023 - spandidos-publications.com
Non-coding RNAs with a length of 22-24 nt are known as microRNAs (miRNAs or miRs),
which are critical regulators of protein translation. Over the past 10 years, the roles of …

Regulation of the key epithelial cancer suppressor miR-124 function by competing endogenous RNAs

EA Braga, MV Fridman, AM Burdennyy… - International journal of …, 2022 - mdpi.com
A decrease in the miR-124 expression was observed in various epithelial cancers. Like a
classical suppressor, miR-124 can inhibit the translation of multiple oncogenic proteins …

Gene methylation of CADM1 and MAL identified as a biomarker of high grade anal intraepithelial neoplasia

S Phillips, K Cassells, SM Garland, DA Machalek… - Scientific Reports, 2022 - nature.com
Human papillomavirus (HPV) is detected in up to 96% of anal squamous cell cancers, where
screening programs needed. However, the best methodology is still undetermined. Host …

A paclitaxel and microRNA-124 coloaded stepped cleavable nanosystem against triple negative breast cancer

C Chen, M Shen, H Liao, Q Guo, H Fu, J Yu… - Journal of …, 2021 - Springer
Background Triple negative breast cancer (TNBC) is one of the most biologically aggressive
breast cancers and lacks effective treatment options, resulting in a poor prognosis …

The miR-124-3p/neuropilin-1 axis contributes to the proliferation and metastasis of triple-negative breast cancer cells and co-activates the TGF-β pathway

J Zhang, X Zhang, Z Li, Q Wang, Y Shi, X Jiang… - Frontiers in …, 2021 - frontiersin.org
Triple-negative breast cancer (TNBC) accounts for 90% of breast cancer-associated
mortality. Neuropilin-1 (NRP-1) acts as a non-tyrosine kinase receptor for several cellular …

[HTML][HTML] Emerging role of non-invasive and liquid biopsy biomarkers in pancreatic cancer

A Bararia, P Chakraborty, P Roy… - World Journal of …, 2023 - ncbi.nlm.nih.gov
A global increase in the incidence of pancreatic cancer (PanCa) presents a major concern
and health burden. The traditional tissue-based diagnostic techniques provided a major way …