Mucosal vaccines—fortifying the frontiers
EC Lavelle, RW Ward - Nature Reviews Immunology, 2022 - nature.com
Mucosal vaccines offer the potential to trigger robust protective immune responses at the
predominant sites of pathogen infection. In principle, the induction of adaptive immunity at …
predominant sites of pathogen infection. In principle, the induction of adaptive immunity at …
Heterogeneity of type 2 innate lymphoid cells
H Spits, J Mjösberg - Nature Reviews Immunology, 2022 - nature.com
More than a decade ago, type 2 innate lymphoid cells (ILC2s) were discovered to be
members of a family of innate immune cells consisting of five subsets that form a first line of …
members of a family of innate immune cells consisting of five subsets that form a first line of …
[HTML][HTML] Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response
The role of innate immune cells in allergen immunotherapy that confers immune tolerance to
the sensitizing allergen is unclear. Here, we report a role of interleukin-10-producing type 2 …
the sensitizing allergen is unclear. Here, we report a role of interleukin-10-producing type 2 …
Plasticity of innate lymphoid cell subsets
Innate lymphoid cells (ILCs) are important for tissue homeostasis and for the initiation of
immune responses. Based on their transcriptional regulation and cytokine profiles, ILCs can …
immune responses. Based on their transcriptional regulation and cytokine profiles, ILCs can …
Control of innate immune response by biomaterial surface topography, energy, and stiffness
JO Abaricia, N Farzad, TJ Heath, J Simmons… - Acta Biomaterialia, 2021 - Elsevier
As the focus of implantable biomaterials has shifted from bioinert implants to bioactive
designs, recent research has highlighted the complex interactions between cell physiologic …
designs, recent research has highlighted the complex interactions between cell physiologic …
[HTML][HTML] Tissue-specific features of innate lymphoid cells
I Meininger, A Carrasco, A Rao, T Soini, E Kokkinou… - Trends in …, 2020 - cell.com
Although the function of the circulating immune cell compartment has been studied in detail
for decades, limitations in terms of access and cell yields from peripheral tissues have …
for decades, limitations in terms of access and cell yields from peripheral tissues have …
Innate lymphoid cells control signaling circuits to regulate tissue-specific immunity
CSN Klose, D Artis - Cell research, 2020 - nature.com
The multifaceted organization of the immune system involves not only patrolling
lymphocytes that constantly monitor antigen-presenting cells in secondary lymphoid organs …
lymphocytes that constantly monitor antigen-presenting cells in secondary lymphoid organs …
c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies
JH Bernink, Y Ohne, MBM Teunissen, J Wang… - Nature …, 2019 - nature.com
Here we identify a group 2 innate lymphoid cell (ILC2) subpopulation that can convert into
interleukin-17 (IL-17)-producing NKp44− ILC3-like cells. c-Kit and CCR6 define this ILC2 …
interleukin-17 (IL-17)-producing NKp44− ILC3-like cells. c-Kit and CCR6 define this ILC2 …
The tumour microenvironment shapes innate lymphoid cells in patients with hepatocellular carcinoma
Objective Hepatocellular carcinoma (HCC) represents a typical inflammation-associated
cancer. Tissue resident innate lymphoid cells (ILCs) have been suggested to control tumour …
cancer. Tissue resident innate lymphoid cells (ILCs) have been suggested to control tumour …
[HTML][HTML] Single-cell analysis reveals innate lymphoid cell lineage infidelity in atopic dermatitis
Background Although ample knowledge exists about phenotype and function of cutaneous T
lymphocytes, much less is known about the lymphocytic components of the skin's innate …
lymphocytes, much less is known about the lymphocytic components of the skin's innate …