Type I interferons and SARS-CoV-2: from cells to organisms

P Bastard, Q Zhang, SY Zhang, E Jouanguy… - Current Opinion in …, 2022 - Elsevier
Type I interferons (IFNs) have broad and potent antiviral activity. We review the interplay
between type I IFNs and SARS-CoV-2. Human cells infected with SARS-CoV-2 in vitro …

SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery

JJ Frere, RA Serafini, KD Pryce, M Zazhytska… - Science translational …, 2022 - science.org
The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection can result in prolonged pathologies collectively referred to as post-acute sequalae …

Challenges and opportunities in long COVID research

RE Hamlin, CA Blish - Immunity, 2024 - cell.com
Long COVID (LC) is a condition in which patients do not fully recover from the initial SARS-
CoV-2 infection but rather have persistent or new symptoms for months to years following …

SARS-CoV-2 Omicron variant causes mild pathology in the upper and lower respiratory tract of hamsters

F Armando, G Beythien, FK Kaiser, L Allnoch… - Nature …, 2022 - nature.com
Since its discovery in 2019, multiple variants of severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) have been identified. This study investigates virus spread and …

[HTML][HTML] Parsing the role of NSP1 in SARS-CoV-2 infection

T Fisher, A Gluck, K Narayanan, M Kuroda… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to shutoff of protein
synthesis, and nsp1, a central shutoff factor in coronaviruses, inhibits cellular mRNA …

Golden Syrian hamster as a model to study cardiovascular complications associated with SARS-CoV-2 infection

ZA Rizvi, R Dalal, S Sadhu, A Binayke, J Dandotiya… - Elife, 2022 - elifesciences.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in the Golden
Syrian hamster causes lung pathology that resembles human coronavirus disease (COVID …

Characterization of SARS-CoV-2 Omicron BA. 2.75 clinical isolates

R Uraki, S Iida, PJ Halfmann, S Yamayoshi… - Nature …, 2023 - nature.com
The prevalence of the Omicron subvariant BA. 2.75 rapidly increased in India and Nepal
during the summer of 2022, and spread globally. However, the virological features of BA …

Intranasal administration of BReC-CoV-2 COVID-19 vaccine protects K18-hACE2 mice against lethal SARS-CoV-2 challenge

TY Wong, KS Lee, BP Russ, AM Horspool, J Kang… - npj Vaccines, 2022 - nature.com
SARS-CoV-2 is a viral respiratory pathogen responsible for the current global pandemic and
the disease that causes COVID-19. All current WHO approved COVID-19 vaccines are …

Transcriptomic profiling of cardiac tissues from SARS‐CoV‐2 patients identifies DNA damage

A Kulasinghe, N Liu, CW Tan, J Monkman… - …, 2023 - Wiley Online Library
The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is known to present
with pulmonary and extra‐pulmonary organ complications. In comparison with the 2009 …

After the virus has cleared—Can preclinical models be employed for Long COVID research?

EB Jansen, SN Orvold, CL Swan, A Yourkowski… - PLoS …, 2022 - journals.plos.org
Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) can cause the life-
threatening acute respiratory disease called COVID-19 (Coronavirus Disease 2019) as well …