Plants in anticancer drug discovery: from molecular mechanism to chemoprevention

AJ Siddiqui, S Jahan, R Singh, J Saxena… - BioMed Research …, 2022 - Wiley Online Library
Cancer is one of the primary causes of mortality globally, and the discovery of new
anticancer drugs is the most important need in recent times. Natural products have been …

Nigella sativa L. (Black Cumin): A Promising Natural Remedy for Wide Range of Illnesses

EM Yimer, KB Tuem, A Karim… - Evidence‐Based …, 2019 - Wiley Online Library
The seed of Nigella sativa (N. sativa) has been used in different civilization around the world
for centuries to treat various animal and human ailments. So far, numerous studies …

Thymoquinone and its therapeutic potentials

S Darakhshan, AB Pour, AH Colagar… - Pharmacological …, 2015 - Elsevier
Herbal medicine has attracted great attention in the recent years and is increasingly used as
alternatives to chemical drugs. Several lines of evidence support the positive impact of …

Spices for prevention and treatment of cancers

J Zheng, Y Zhou, Y Li, DP Xu, S Li, HB Li - Nutrients, 2016 - mdpi.com
Spices have been widely used as food flavorings and folk medicines for thousands of years.
Numerous studies have documented the antioxidant, anti-inflammatory and …

[HTML][HTML] Black cumin (Nigella sativa) and its constituent (thymoquinone): a review on antimicrobial effects

F Forouzanfar, BSF Bazzaz… - Iranian journal of basic …, 2014 - ncbi.nlm.nih.gov
Nigella sativa seeds have wide therapeutic effects and have been reported to have
significant effects against many ailments such as skin diseases, jaundice, gastrointestinal …

Thymoquinone: potential cure for inflammatory disorders and cancer

CC Woo, AP Kumar, G Sethi, KHB Tan - Biochemical pharmacology, 2012 - Elsevier
Thymoquinone is an active ingredient isolated from Nigella sativa and has been
investigated for its anti-oxidant, anti-inflammatory and anticancer activities in both in vitro …

[HTML][HTML] Thymoquinone, as an anticancer molecule: from basic research to clinical investigation

MA Khan, M Tania, S Fu, J Fu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Thymoquinone is an anticancer phytochemical commonly found in black cumin. In this
review, we discuss the potential of thymoquinone as anticancer molecule, its mechanism of …

Cancer prevention with natural compounds

NP Gullett, ARMR Amin, S Bayraktar, JM Pezzuto… - Seminars in …, 2010 - Elsevier
Botanical and nutritional compounds have been used for the treatment of cancer throughout
history. These compounds also may be useful in the prevention of cancer. Population …

Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa

AF Majdalawieh, MW Fayyad… - Critical reviews in food …, 2017 - Taylor & Francis
Over the past two decades, studies have documented the wide-range anti-cancer effects of
Nigella sativa, known as black seed or black cumin. Thymoquinone (TQ), its major active …

Revisiting pharmacological potentials of Nigella sativa seed: A promising option for COVID‐19 prevention and cure

MN Islam, KS Hossain, PP Sarker… - Phytotherapy …, 2021 - Wiley Online Library
Nigella sativa seed and its active compounds have been historically recognized as an
effective herbal panacea that can establish a balanced inflammatory response by …