Genetics of lupus nephritis: clinical implications

ME Munroe, JA James - Seminars in nephrology, 2015 - Elsevier
Systemic lupus erythematosus is a heterogeneous autoimmune disease marked by the
presence of pathogenic autoantibodies, immune dysregulation, and chronic inflammation …

Organ-specific biomarkers in lupus

H Wu, J Zeng, J Yin, Q Peng, M Zhao, Q Lu - Autoimmunity reviews, 2017 - Elsevier
Systemic lupus erythematosus (SLE) is a complex and highly heterogeneous disease, which
affects multiple organs, including joints, skin, kidneys, heart, hematopoietic system, and …

Biomarker profiling for lupus nephritis

Y Li, X Fang, QZ Li - Genomics, proteomics & bioinformatics, 2013 - academic.oup.com
Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus
erythematosus (SLE), which is associated with significant morbidity and mortality of SLE …

Blood pressure and renal hemodynamic responses to acute angiotensin II infusion are enhanced in a female mouse model of systemic lupus erythematosus

M Venegas-Pont, KW Mathis, R Iliescu… - American Journal …, 2011 - journals.physiology.org
Inflammation and immune system dysfunction contributes to the development of
cardiovascular and renal disease. Systemic lupus erythematosus (SLE) is a chronic …

Novel biomarkers for systemic lupus erythematosus

J Zeng, H Wu, M Zhao, Q Lu - Biomarkers in Medicine, 2017 - Taylor & Francis
Systemic lupus erythematosus (SLE) is a complex and highly heterogeneous disease. By
now, no novel drug has been approved by the US FDA in the past 50 years, except …

[HTML][HTML] HLA-DRB1 alleles in juvenile-onset systemic lupus erythematosus: renal histologic class correlations

BL Liphaus, MHB Kiss, AC Goldberg - Brazilian journal of medical …, 2007 - SciELO Brasil
Human leukocyte antigens (HLA) DRB1* 03 and DRB1* 02 have been associated with
systemic lupus erythematosus (SLE) in Caucasians and black populations. It has been …

Genetics of human lupus nephritis

L Morel - Seminars in nephrology, 2007 - Elsevier
Systemic lupus erythematosus (SLE) is a prototypic systemic autoimmune disease in which
glomerulonephritis represents one of the most severe clinical presentations. Numerous …

The beneficial role of vitamin D in systemic lupus erythematosus (SLE)

K vinh quốc Lương, LTH Nguyễn - Clinical rheumatology, 2012 - Springer
Patients with systemic lupus erythematosus (SLE) have a high prevalence of abnormal bone
metabolism and vitamin D deficiency. Genetic studies have provided the opportunity to …

Association of angiotensin‐converting enzyme insertion/deletion polymorphism with susceptibility to systemic lupus erythematosus: a meta‐analysis

AF Huang, H Li, L Ke, C Yang, XY Liu… - International Journal …, 2018 - Wiley Online Library
Background The aim of this study was to determine whether the angiotensin‐converting
enzyme (ACE) insertion/deletion (I/D) gene polymorphism confers susceptibility to systemic …

Association between the angiotensin-converting enzyme insertion/deletion polymorphism and susceptibility to systemic lupus erythematosus: a meta-analysis

YH Lee, SJ Choi, JD Ji… - Journal of the Renin …, 2013 - journals.sagepub.com
Objective: The aim of this study was to determine whether the insertion (I)/deletion (D)
polymorphism within intron 16 of angiotensin-converting enzyme (ACE) confers …