Rare mutations of the FOXP2 transcription factor gene cause a monogenic syndrome
characterized by impaired speech development and linguistic deficits. Recent genomic …

Any account of “what is special about the human brain”(Passingham 2008) must specify the
neural basis of our unique ability to produce speech and delineate how these remarkable …

During the first year of life, infants pass important milestones in language development. We
review some of the experimental evidence concerning these milestones in the domains of …

The evolution of novel morphological features, such as feathers, involves the modification of
developmental processes regulated by gene networks. The fact that genetic novelty …

FOXP transcription factors are an evolutionarily ancient protein subfamily coordinating the
development of several organ systems in the vertebrate body. Association of their genes …

Mutations of the FOXP2 gene impair speech and language development in humans and
shRNA-mediated suppression of the avian ortholog FoxP2 disrupts song learning in juvenile …

INTRODUCTION Brain activity drives both behavior and regulated gene expression in
neurons. Although past studies have identified activity-induced signaling and gene …

It is a challenge to identify the molecular networks contributing to the neural basis of human
speech. Mutations in transcription factor FOXP2 cause difficulties mastering fluent speech …

Similarities between speech and birdsong make songbirds advantageous for investigating
the neurogenetics of learned vocal communication—a complex phenotype probably …

Autism spectrum disorders (ASD) is a neurodevelopmental disease with complex genetics;
however, the genes that are responsible for this disease still remain mostly unknown. Here …