BDNF and memory processing

P Bekinschtein, M Cammarota, JH Medina - Neuropharmacology, 2014 - Elsevier
Brain-derived neurotrophic factor has emerged as one of the most important molecules
involved in memory. Its wide role in different types of memories that depend on different …

Epigenetic regulation of the BDNF gene: implications for psychiatric disorders

F Boulle, DLA Van Den Hove, SB Jakob… - Molecular …, 2012 - nature.com
Abnormal brain-derived neurotrophic factor (BDNF) signaling seems to have a central role in
the course and development of various neurological and psychiatric disorders. In addition …

Stress and trauma: BDNF control of dendritic-spine formation and regression

MR Bennett, J Lagopoulos - Progress in neurobiology, 2014 - Elsevier
Chronic restraint stress leads to increases in brain derived neurotrophic factor (BDNF)
mRNA and protein in some regions of the brain, eg the basal lateral amygdala (BLA) but …

DNA methyltransferases, DNA methylation, and age-associated cognitive function

D Cui, X Xu - International journal of molecular sciences, 2018 - mdpi.com
Ageing, a leading cause of the decline/deficits in human learning, memory, and cognitive
abilities, is a major risk factor for age-associated neurodegenerative disorders such as …

A brief primer on the mediational role of BDNF in the exercise‐memory link

PD Loprinzi, E Frith - Clinical physiology and functional imaging, 2019 - Wiley Online Library
One of the most amazing aspects of the human brain is its ability to learn information and
use it to change behaviour. A key neurotrophin that influences memory function is brain …

An epigenetic framework for neurodevelopmental disorders: from pathogenesis to potential therapy

MJ Millan - Neuropharmacology, 2013 - Elsevier
Neurodevelopmental disorders (NDDs) are characterized by aberrant and delayed early-life
development of the brain, leading to deficits in language, cognition, motor behaviour and …

Prenatal stress decreases Bdnf expression and increases methylation of Bdnf exon IV in rats

GJ Boersma, RS Lee, ZA Cordner, ER Ewald… - Epigenetics, 2014 - Taylor & Francis
There is ample evidence that exposure to stress during gestation increases the risk of the
offspring to develop mood disorders. Brain-derived neurotrophic factor (Bdnf) plays a critical …

Dynamic DNA methylation: a prime candidate for genomic metaplasticity and behavioral adaptation

D Baker-Andresen, VS Ratnu, TW Bredy - Trends in neurosciences, 2013 - cell.com
DNA methylation was once considered to be a static epigenetic modification whose primary
function was restricted to directing the development of cellular phenotype. However, it is now …

Chromatin remodeling—a novel strategy to control excessive alcohol drinking

V Warnault, E Darcq, A Levine, S Barak… - Translational psychiatry, 2013 - nature.com
Harmful excessive use of alcohol has a severe impact on society and it remains one of the
major causes of morbidity and mortality in the population. However, mechanisms that …

Epigenetic mechanisms of memory formation and reconsolidation

TJ Jarome, FD Lubin - Neurobiology of learning and memory, 2014 - Elsevier
Memory consolidation involves transcriptional control of genes in neurons to stabilize a
newly formed memory. Following retrieval, a once consolidated memory destabilizes and …