Stem cell-derived organoid models for SARS-CoV-2 and its molecular interaction with host cells

L Dawoody Nejad, LM Julian - Molecular Biology Reports, 2023 - Springer
Modeling severe acute respiratory syndrome, Coronavirus 2 (SARS-CoV-2) infection in stem
cell-derived organoids has helped in our understanding of the molecular pathogenesis of …

Cytokine production in an ex vivo model of SARS-CoV-2 lung infection

DA Vorobyeva, DM Potashnikova… - Frontiers in …, 2024 - frontiersin.org
Introduction The mechanisms of the SARS-CoV-2-triggered complex alterations in immune
cell activation and production of cytokines in lung tissue remain poorly understood, in part …

Characterizing Infections in Two Epidemic Waves of SARS-CoV-2 Omicron Variants: A Cohort Study in Guangzhou, China

L Qu, C Xie, M Qiu, L Yi, Z Liu, L Zou, P Hu, H Jiang… - Viruses, 2024 - mdpi.com
Background: After the adjustment of COVID-19 epidemic policy, mainland China
experienced two consecutive waves of Omicron variants within a seven-month period. In …

How Chinese Researchers Face Ethical and Social Challenges in Human Organoid Research and Applications: a Questionnaire Study

H Luo, Y Yu, G Li, Y Ma - Asian Bioethics Review, 2024 - Springer
The utilisation of human organoids has the potential to expedite the cycle of biological
innovation significantly, yet it also raises a series of ethical and societal concerns. This study …

Field-effect Transistor Biosensors for Rapid SARS-CoV-2 Detection

A Ibijbijen, F Besbes, H Korri-Youssoufi - 2024 - books.rsc.org
The COVID-19 pandemic has an unprecedented global effect and brought about a
significant change in the healthcare industry. With the increasing demand for accurate and …

Repurposing Inhaled Ibuprofenate, a Non Steroidal Anti‐Inflammatory Drug, as a Potential Adjuvant Treatment for Pneumonia, CARDS and its Aetiological Agent …

CC Zurita‐Lizza, I Rodriguez‐Sanchez… - Clinical and …, 2023 - Wiley Online Library
In this manuscript, we will describe and highlight the most important potential underlying
mechanisms of action of the inhaled sodium ibuprofenate in hypertonic saline formulation …

Challenges in the Detection of Emerging Novel Pathogens and Evolving Known Pathogens

NA Shamsusah, MEI Mohd Fadli, R Emrizal… - 2024 - books.rsc.org
Within the span of slightly over a century, many epidemics had escaped regional
containment to become pandemics. At the time of writing, the most recent pandemic, COVID …