Heavy metals and human health: mechanistic insight into toxicity and counter defense system of antioxidants

AT Jan, M Azam, K Siddiqui, A Ali, I Choi… - International journal of …, 2015 - mdpi.com
Heavy metals, which have widespread environmental distribution and originate from natural
and anthropogenic sources, are common environmental pollutants. In recent decades, their …

Mechanisms of methylmercury-induced neurotoxicity: evidence from experimental studies

M Farina, JBT Rocha, M Aschner - Life sciences, 2011 - Elsevier
Neurological disorders are common, costly, and can cause enduring disability. Although
mostly unknown, a few environmental toxicants are recognized causes of neurological …

Mercury involvement in neuronal damage and in neurodegenerative diseases

VL Cariccio, A Samà, P Bramanti, E Mazzon - Biological trace element …, 2019 - Springer
Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease,
amyotrophic lateral sclerosis, and multiple sclerosis are characterized by a chronic and …

Oxidative stress in MeHg-induced neurotoxicity

M Farina, M Aschner, JBT Rocha - Toxicology and applied pharmacology, 2011 - Elsevier
Methylmercury (MeHg) is an environmental toxicant that leads to long-lasting neurological
and developmental deficits in animals and humans. Although the molecular mechanisms …

[HTML][HTML] Metal elements and pesticides as risk factors for Parkinson's disease-A review

I Ullah, L Zhao, Y Hai, M Fahim, D Alwayli, X Wang… - Toxicology reports, 2021 - Elsevier
Essential metals including iron (Fe) and manganese (Mn) with known physiological
functions in human body play an important role in cell homeostasis. Excessive exposure to …

Methylmercury induced ferroptosis by interference of iron homeostasis and glutathione metabolism in CTX cells

X Xu, SS Wang, L Zhang, AX Lu, Y Lin, JX Liu… - Environmental …, 2023 - Elsevier
Environmental methylmercury (MeHg) exposure has gained global attention owing to its
serious health hazards, especially neurotoxicity. Ferroptosis is a novel form of programmed …

[HTML][HTML] Comparative study on methyl-and ethylmercury-induced toxicity in C6 glioma cells and the potential role of LAT-1 in mediating mercurial-thiol complexes …

LT Zimmermann, DB Santos, AA Naime, RB Leal… - Neurotoxicology, 2013 - Elsevier
Various forms of mercury possess different rates of absorption, metabolism and excretion,
and consequently, toxicity. Methylmercury (MeHg) is a highly neurotoxic organic mercurial …

Sources and toxicity of mercury in the San Francisco Bay area, spanning California and beyond

M Kolipinski, M Subramanian, K Kristen… - … and Public Health, 2020 - Wiley Online Library
This report synthesizes and evaluates published scientific literature on the environmental
occurrence and biomagnification of mercury with emphasis on the San Francisco Bay Area …

Adverse effects of methylmercury (MeHg) on life parameters, antioxidant systems, and MAPK signaling pathways in the copepod Tigriopus japonicus

YH Lee, HM Kang, DH Kim, M Wang, CB Jeong… - Aquatic Toxicology, 2017 - Elsevier
Methylmercury (MeHg) is a concerning environmental pollutant that bioaccumulates and
biomagnifies in the aquatic food web. However, the effects of MeHg on marine zooplankton …

Role of low-proportion, hydrophobic dissolved organic matter components in inhibiting methylmercury uptake by phytoplankton

Z Li, Z Wu, S Bo, J Chi, X Cui, W He, X Cui, Y Liu… - Chemosphere, 2024 - Elsevier
Uptake of methylmercury (MeHg), a potent neurotoxin, by phytoplankton is a major concern
due to its role as the primary pathway for MeHg entry into aquatic food webs, thereby posing …