Diabetes and cognitive dysfunction

RJ McCrimmon, CM Ryan, BM Frier - The Lancet, 2012 - thelancet.com
Cognitive dysfunction in type 1 and type 2 diabetes share many similarities, but important
differences do exist. A primary distinguishing feature of type 2 diabetes is that people with …

Metabolism: a novel shared link between diabetes mellitus and Alzheimer's disease

Y Sun, C Ma, H Sun, H Wang, W Peng… - Journal of diabetes …, 2020 - Wiley Online Library
As a chronic metabolic disease, diabetes mellitus (DM) is broadly characterized by elevated
levels of blood glucose. Novel epidemiological studies demonstrate that some diabetic …

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

Y Liu, F Liu, I Grundke‐Iqbal, K Iqbal… - The Journal of …, 2011 - Wiley Online Library
Brain glucose metabolism is impaired in Alzheimer's disease (AD), the most common form of
dementia. Type 2 diabetes mellitus (T2DM) is reported to increase the risk for dementia …

The role of glucose transporters in brain disease: diabetes and Alzheimer's disease

K Shah, S DeSilva, T Abbruscato - International journal of molecular …, 2012 - mdpi.com
The occurrence of altered brain glucose metabolism has long been suggested in both
diabetes and Alzheimer's diseases. However, the preceding mechanism to altered glucose …

Diabetes and risk of Parkinson's disease: a systematic review and meta-analysis

E Cereda, M Barichella, C Pedrolli, C Klersy… - Diabetes …, 2011 - Am Diabetes Assoc
OBJECTIVE Diabetes has been associated with chronic neurodegeneration. We performed
a systematic review and meta-analysis to assess the relationship between pre-existing …

Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer's disease and diabetes interrelation

SC Correia, RX Santos, C Carvalho, S Cardoso… - Brain research, 2012 - Elsevier
Many epidemiological studies have shown that diabetes, particularly type 2 diabetes,
significantly increases the risk to develop Alzheimer's disease. Both diseases share several …

Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease?

SC Correia, RX Santos, G Perry, X Zhu, PI Moreira… - Ageing research …, 2011 - Elsevier
Severe abnormalities in brain glucose/energy metabolism and insulin signaling have been
documented to take a pivotal role in early sporadic Alzheimer's disease (sAD) pathology …

Connecting Alzheimer's disease to diabetes: underlying mechanisms and potential therapeutic targets

MNN Vieira, RAS Lima-Filho, FG De Felice - Neuropharmacology, 2018 - Elsevier
Alzheimer's disease (AD) is a risk factor for type 2 diabetes and vice versa, and a growing
body of evidence indicates that these diseases are connected both at epidemiological …

[HTML][HTML] Association between Parkinson's disease and diabetes mellitus: From epidemiology, pathophysiology and prevention to treatment

H Yu, T Sun, X He, Z Wang, K Zhao, J An, L Wen… - Aging and …, 2022 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) and Parkinson's disease (PD) are both age-related diseases of
global concern being among the most common chronic metabolic and neurodegenerative …

[HTML][HTML] Glucose metabolism impairment in Parkinson's disease

C Dai, C Tan, L Zhao, Y Liang, G Liu, H Liu… - Brain research …, 2023 - Elsevier
Impairments in systematic and regional glucose metabolism exist in patients with
Parkinson's disease (PD) at every stage of the disease course, and such impairments are …