Mitochondrial respiratory chain complexes

JS Sousa, E D'Imprima, J Vonck - Membrane protein complexes: structure …, 2018 - Springer
Mitochondria are the power stations of the eukaryotic cell, using the energy released by the
oxidation of glucose and other sugars to produce ATP. Electrons are transferred from NADH …

Mitochondrial respiratory chain dysfunction: implications in neurodegeneration

M Morán, D Moreno-Lastres, L Marín-Buera… - Free Radical Biology …, 2012 - Elsevier
For decades mitochondria have been considered static round-shaped organelles in charge
of energy production. In contrast, they are highly dynamic cellular components that undergo …

Mitochondrial protein synthesis, import, and assembly

TD Fox - Genetics, 2012 - academic.oup.com
The mitochondrion is arguably the most complex organelle in the budding yeast cell
cytoplasm. It is essential for viability as well as respiratory growth. Its innermost aqueous …

Blackout in the powerhouse: clinical phenotypes associated with defects in the assembly of OXPHOS complexes and the mitoribosome

DH Hock, DRL Robinson, DA Stroud - Biochemical Journal, 2020 - portlandpress.com
Mitochondria produce the bulk of the energy used by almost all eukaryotic cells through
oxidative phosphorylation (OXPHOS) which occurs on the four complexes of the respiratory …

[HTML][HTML] Assembly of F1F0-ATP synthases

T Rühle, D Leister - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2015 - Elsevier
Abstract F 1 F 0-ATP synthases are multimeric protein complexes and common prerequisites
for their correct assembly are (i) provision of subunits in appropriate relative amounts,(ii) …

Modular biogenesis of mitochondrial respiratory complexes

MH Barros, GP McStay - Mitochondrion, 2020 - Elsevier
Mitochondrial function relies on the activity of oxidative phosphorylation to synthesise ATP
and generate an electrochemical gradient across the inner mitochondrial membrane. These …

[HTML][HTML] Regulation of mitochondrial ATP synthase in cardiac pathophysiology

Q Long, K Yang, Q Yang - American journal of cardiovascular …, 2015 - ncbi.nlm.nih.gov
Mitochondrial function is paramount to energy homeostasis, metabolism, signaling, and
apoptosis in cells. Mitochondrial complex V (ATP synthase), a molecular motor, is the …

The 3 × 120° rotary mechanism of Paracoccus denitrificans F1-ATPase is different from that of the bacterial and mitochondrial F1-ATPases

M Zarco-Zavala, R Watanabe… - Proceedings of the …, 2020 - National Acad Sciences
The rotation of Paracoccus denitrificans F1-ATPase (PdF1) was studied using single-
molecule microscopy. At all concentrations of adenosine triphosphate (ATP) or a slowly …

Modular assembly of yeast mitochondrial ATP synthase and cytochrome oxidase

LVR Franco, CH Su, A Tzagoloff - Biological Chemistry, 2020 - degruyter.com
The respiratory pathway of mitochondria is composed of four electron transfer complexes
and the ATP synthase. In this article, we review evidence from studies of Saccharomyces …

Knockdown of DAPIT (diabetes-associated protein in insulin-sensitive tissue) results in loss of ATP synthase in mitochondria

S Ohsakaya, M Fujikawa, T Hisabori… - Journal of Biological …, 2011 - ASBMB
It was found recently that a diabetes-associated protein in insulin-sensitive tissue (DAPIT) is
associated with mitochondrial ATP synthase. Here, we report that the suppressed …