CRISPR/Cas-powered nanobiosensors for diagnostics
QA Phan, LB Truong, D Medina-Cruz, C Dincer… - Biosensors and …, 2022 - Elsevier
CRISPR diagnostics (CRISPR-Dx) offer a wide range of enhancements compared to
traditional nanobiosensors by taking advantage of the excellent trans-cleavage activity of the …
traditional nanobiosensors by taking advantage of the excellent trans-cleavage activity of the …
[HTML][HTML] Exploring nano-enabled CRISPR-Cas-powered strategies for efficient diagnostics and treatment of infectious diseases
Biomedical researchers have subsequently been inspired the development of new
approaches for precisely changing an organism's genomic DNA in order to investigate …
approaches for precisely changing an organism's genomic DNA in order to investigate …
COVID-19: clinical presentation and detection methods
M Pradhan, K Shah, A Alexander… - … of Immunoassay and …, 2022 - Taylor & Francis
The unending outburst of COVID-19 has reinforced the necessity of SARS-CoV-2
identification approaches for the prevention of infection transmission and the proper care of …
identification approaches for the prevention of infection transmission and the proper care of …
[HTML][HTML] Application of CRISPR/Cas9 in Alzheimer's disease
L Lu, X Yu, Y Cai, M Sun, H Yang - Frontiers in neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder
clinically characterized by cognitive impairment, abnormal behavior, and social deficits …
clinically characterized by cognitive impairment, abnormal behavior, and social deficits …
[HTML][HTML] Delivery of RNAs to specific organs by lipid nanoparticles for gene therapy
K Godbout, JP Tremblay - Pharmaceutics, 2022 - mdpi.com
Gene therapy holds great promise in the treatment of genetic diseases. It is now possible to
make DNA modifications using the CRISPR system. However, a major problem remains: the …
make DNA modifications using the CRISPR system. However, a major problem remains: the …
[HTML][HTML] CRISPR applications in cancer diagnosis and treatment
M Wang, M Chen, X Wu, X Huang, B Yu - Cellular & Molecular Biology …, 2023 - Springer
Cancer remains a significant global health challenge, necessitating the exploration of novel
and more precise therapeutic options beyond conventional treatments. In this regard …
and more precise therapeutic options beyond conventional treatments. In this regard …
[HTML][HTML] Research progress and application of the CRISPR/Cas9 gene-editing technology based on hepatocellular carcinoma
S Yu, R Zhao, B Zhang, C Lai, L Li, J Shen… - Asian Journal of …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is now a common cause of cancer death, with no obvious
change in patient survival over the past few years. Although the traditional therapeutic …
change in patient survival over the past few years. Although the traditional therapeutic …
[HTML][HTML] CRISPR-Cas and its wide-ranging applications: From human genome editing to environmental implications, technical limitations, hazards and bioethical …
R Piergentili, A Del Rio, F Signore, F Umani Ronchi… - Cells, 2021 - mdpi.com
The CRISPR-Cas system is a powerful tool for in vivo editing the genome of most organisms,
including man. During the years this technique has been applied in several fields, such as …
including man. During the years this technique has been applied in several fields, such as …
[HTML][HTML] Recent advances in genome-engineering strategies
MA Boti, K Athanasopoulou, PG Adamopoulos… - Genes, 2023 - mdpi.com
In October 2020, the chemistry Nobel Prize was awarded to Emmanuelle Charpentier and
Jennifer A. Doudna for the discovery of a new promising genome-editing tool: the genetic …
Jennifer A. Doudna for the discovery of a new promising genome-editing tool: the genetic …
A review on molecular scissoring with CRISPR/Cas9 genome editing technology
M Irfan, H Majeed, T Iftikhar, PK Ravi - Toxicology Research, 2024 - academic.oup.com
Genome editing is a technology to make specific changes in the DNA of a cell or an
organism. It has significantly altered the landscape of life sciences, facilitating the …
organism. It has significantly altered the landscape of life sciences, facilitating the …