CRISPR/Cas-powered nanobiosensors for diagnostics

QA Phan, LB Truong, D Medina-Cruz, C Dincer… - Biosensors and …, 2022 - Elsevier
CRISPR diagnostics (CRISPR-Dx) offer a wide range of enhancements compared to
traditional nanobiosensors by taking advantage of the excellent trans-cleavage activity of the …

[HTML][HTML] Exploring nano-enabled CRISPR-Cas-powered strategies for efficient diagnostics and treatment of infectious diseases

AK Dubey, V Kumar Gupta, M Kujawska… - Journal of Nanostructure …, 2022 - Springer
Biomedical researchers have subsequently been inspired the development of new
approaches for precisely changing an organism's genomic DNA in order to investigate …

COVID-19: clinical presentation and detection methods

M Pradhan, K Shah, A Alexander… - … of Immunoassay and …, 2022 - Taylor & Francis
The unending outburst of COVID-19 has reinforced the necessity of SARS-CoV-2
identification approaches for the prevention of infection transmission and the proper care of …

[HTML][HTML] Application of CRISPR/Cas9 in Alzheimer's disease

L Lu, X Yu, Y Cai, M Sun, H Yang - Frontiers in neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder
clinically characterized by cognitive impairment, abnormal behavior, and social deficits …

[HTML][HTML] Delivery of RNAs to specific organs by lipid nanoparticles for gene therapy

K Godbout, JP Tremblay - Pharmaceutics, 2022 - mdpi.com
Gene therapy holds great promise in the treatment of genetic diseases. It is now possible to
make DNA modifications using the CRISPR system. However, a major problem remains: the …

[HTML][HTML] CRISPR applications in cancer diagnosis and treatment

M Wang, M Chen, X Wu, X Huang, B Yu - Cellular & Molecular Biology …, 2023 - Springer
Cancer remains a significant global health challenge, necessitating the exploration of novel
and more precise therapeutic options beyond conventional treatments. In this regard …

[HTML][HTML] Research progress and application of the CRISPR/Cas9 gene-editing technology based on hepatocellular carcinoma

S Yu, R Zhao, B Zhang, C Lai, L Li, J Shen… - Asian Journal of …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is now a common cause of cancer death, with no obvious
change in patient survival over the past few years. Although the traditional therapeutic …

[HTML][HTML] CRISPR-Cas and its wide-ranging applications: From human genome editing to environmental implications, technical limitations, hazards and bioethical …

R Piergentili, A Del Rio, F Signore, F Umani Ronchi… - Cells, 2021 - mdpi.com
The CRISPR-Cas system is a powerful tool for in vivo editing the genome of most organisms,
including man. During the years this technique has been applied in several fields, such as …

[HTML][HTML] Recent advances in genome-engineering strategies

MA Boti, K Athanasopoulou, PG Adamopoulos… - Genes, 2023 - mdpi.com
In October 2020, the chemistry Nobel Prize was awarded to Emmanuelle Charpentier and
Jennifer A. Doudna for the discovery of a new promising genome-editing tool: the genetic …

A review on molecular scissoring with CRISPR/Cas9 genome editing technology

M Irfan, H Majeed, T Iftikhar, PK Ravi - Toxicology Research, 2024 - academic.oup.com
Genome editing is a technology to make specific changes in the DNA of a cell or an
organism. It has significantly altered the landscape of life sciences, facilitating the …