Sulforaphane: A review of its therapeutic potentials, advances in its nanodelivery, recent patents, and clinical trials
Traditionally, herbal supplements have shown an exceptional potential of desirability for the
prevention of diseases and their treatment. Sulforaphane (SFN), an organosulfur compound …
prevention of diseases and their treatment. Sulforaphane (SFN), an organosulfur compound …
Targeting the Nrf2 signaling pathway using phytochemical ingredients: A novel therapeutic road map to combat neurodegenerative diseases
X Bai, Z Bian, M Zhang - Phytomedicine, 2023 - Elsevier
Background Nuclear factor erythroid 2-related factor 2 (Nrf2) is a classical nuclear
transcription factor that regulates the system's anti-oxidative stress response. The activation …
transcription factor that regulates the system's anti-oxidative stress response. The activation …
Lipid-nanopotentiated combinatorial delivery of tamoxifen and sulforaphane: ex vivo, in vivo and toxicity studies
Aim: This study aims to load tamoxifen (TAM) and sulforaphane (SFN) into nanostructured
lipid carriers (NLCs) to enhance their oral delivery. Materials & methods: TAM-SFN-NLCs …
lipid carriers (NLCs) to enhance their oral delivery. Materials & methods: TAM-SFN-NLCs …
[HTML][HTML] Systematic development and validation of RP-HPLC method for simultaneous estimation of tamoxifen and sulphoraphane with specific application for …
Abstract Tamoxifen (TAM) and Sulphoraphane (SFN) are well-known anti-estrogen drugs
used for the treatment of breast cancer. Due to their synergistic therapeutic potential, their …
used for the treatment of breast cancer. Due to their synergistic therapeutic potential, their …
Insights for applying erythrosine B as a green fluorescence probe for estimation of anticancer tamoxifen and its analog; clomiphene in nanogram concentration
The growth of tumor tissue is extremely pervasive among post-menopausal women.
Commonly, from the clinical application, adjuvant selective estrogen receptor modulators …
Commonly, from the clinical application, adjuvant selective estrogen receptor modulators …
Analysis of tamoxifen and its main metabolites in plasma samples of breast cancer survivor female athletes: Multivariate and chemometric optimization
T Sadeghcheh, M Saber Tehrani… - Journal of …, 2022 - Wiley Online Library
A sensitive method based on liquid chromatography combined with a diode array detector
was developed and validated to simultaneously determine tamoxifen, and its active …
was developed and validated to simultaneously determine tamoxifen, and its active …
A validated bioanalytical method for the simultaneous estimation of telmisartan and gallic acid in rat plasma samples by high‐performance thin‐layer chromatography …
SK Pattanik, KK Pradhan - Biomedical Chromatography, 2024 - Wiley Online Library
A novel and cost‐effective high‐performance thin‐layer chromatography (HPTLC) method,
combined with densitometric quantification, was developed for the biomedical analysis of …
combined with densitometric quantification, was developed for the biomedical analysis of …
Development of a “turn off–on” whole‐cell biosensor for sulforaphane detection based on the ultrasensitive activator HrpRS
R Li, S Chen, Y Li, X Chen… - Biotechnology and Applied …, 2023 - Wiley Online Library
Sulforaphane (SFN), a defense secondary metabolite, can be used to predict the health
status of plants and also has pharmacological effects, including anticancer, antioxidant, and …
status of plants and also has pharmacological effects, including anticancer, antioxidant, and …
Computer aided design, synthesis and characterisation of thiazolidinedione acetic acid derivatives as brest-cancer inhibitors
R Dubey, KS Patel - Brazilian Journal of Development, 2024 - ojs.brazilianjournals.com.br
The development of new anti-cancer drugs is a dynamic process that is continuously fueled,
at the basic level, by the identification of new molecular targets for chemotherapeutic …
at the basic level, by the identification of new molecular targets for chemotherapeutic …
Nontargeted Metabolomics by High-Resolution Mass Spectrometry to Study the In Vitro Metabolism of a Dual Inverse Agonist of Estrogen-Related Receptors β and γ …
SE Kim, SB Ji, E Kim, M Jeong, J Kim, GM Lee, HJ Seo… - Pharmaceutics, 2021 - mdpi.com
DN203368 ((E)-3-[1-(4-[4-isopropylpiperazine-1-yl] phenyl) 3-methyl-2-phenylbut-1-en-1-yl]
phenol) is a 4-hydroxy tamoxifen analog that is a dual inverse agonist of estrogen-related …
phenol) is a 4-hydroxy tamoxifen analog that is a dual inverse agonist of estrogen-related …