The placenta is the chief regulator of nutrient supply to the growing embryo during gestation.
As such, adequate placental function is instrumental for developmental progression …

In humans, cell fusion is restricted to only a few cell types under normal conditions. In the
placenta, cell fusion is a critical process for generating syncytiotrophoblast: the giant …

Remodeling of the uterine vasculature by invasive extravillous trophoblasts (EVTs) is a
critical aspect of human placentation. Insufficient EVT invasion can lead to severe obstetrical …

Preeclampsia (PE) is a complex, hypertensive disorder of pregnancy, demonstrating
considerable variability in maternal symptoms and fetal outcomes. Unfortunately, prior …

During human development, a temporary organ is formed, the placenta, which invades the
uterine wall to support nutrient, oxygen, and waste exchange between the mother and fetus …

A major unresolved issue is how the uterus influences infertility and subfertility in cattle.
Serial embryo transfer was previously used to classify heifers as high-fertile (HF), subfertile …

Mononuclear cytotrophoblasts of the human placenta proliferate rapidly, subsequently fuse,
and differentiate to form multinucleated syncytiotrophoblast with induction of aromatase …

Background Preeclampsia (PE) is a life-threatening hypertensive pathology of pregnancy
affecting 3–5% of all pregnancies. To date, PE has no cure, early detection markers, or …

Placental dysfunction refers to the insufficiency of placental perfusion and chronic hypoxia
during early pregnancy, which impairs placental function and causes inadequate supply of …

Preeclampsia (PE) is a pregnancy-specific disorder characterized by hypertension and
proteinuria after 20 wk gestation. Abnormal extravillous trophoblast (EVT) invasion and …