[HTML][HTML] Engineered smart materials for RNA based molecular therapy to treat Glioblastoma
Glioblastoma (GBM) is an aggressive malignancy of the central nervous system (CNS) that
remains incurable despite the multitude of improvements in cancer therapeutics. The …
remains incurable despite the multitude of improvements in cancer therapeutics. The …
[HTML][HTML] Harnessing Sulforaphane Potential as a Chemosensitizing Agent: A Comprehensive Review
Simple Summary Recent oncological research highlights the promising role of naturally
derived compounds in cancer prevention and treatment. Sulforaphane (SFN), a …
derived compounds in cancer prevention and treatment. Sulforaphane (SFN), a …
Effects of Sulforaphane on SARS‑CoV‑2 infection and NF‑κB dependent expression of genes involved in the COVID‑19 'cytokine storm'
J Gasparello, G Marzaro, C Papi… - International …, 2023 - spandidos-publications.com
Since its spread at the beginning of 2020, the coronavirus disease 2019 (COVID‑19)
pandemic represents one of the major health problems. Despite the approval, testing, and …
pandemic represents one of the major health problems. Despite the approval, testing, and …
Multiple therapeutic approaches of glioblastoma multiforme: From terminal to therapy
Glioblastoma multiforme (GBM) is an aggressive brain cancer showing poor prognosis.
Currently, treatment methods of GBM are limited with adverse outcomes and low survival …
Currently, treatment methods of GBM are limited with adverse outcomes and low survival …
[HTML][HTML] Peptide nucleic acid conjugates and their antimicrobial applications—a mini-review
U Tsylents, I Siekierska, J Trylska - European Biophysics Journal, 2023 - Springer
Peptide nucleic acid (PNA) is a nucleic acid mimic with high specificity and binding affinity to
natural DNA or RNA, as well as resistance to enzymatic degradation. PNA sequences can …
natural DNA or RNA, as well as resistance to enzymatic degradation. PNA sequences can …
[HTML][HTML] A comprehensive review on function of miR-15b-5p in malignant and non-malignant disorders
miR-15b-5p is encoded by MIR15B gene. This gene is located on cytogenetic band 3q25.
33. This miRNA participates in the pathogenesis of several cancers as well as non …
33. This miRNA participates in the pathogenesis of several cancers as well as non …
[HTML][HTML] MicroRNAs miR-584-5p and miR-425-3p are up-regulated in plasma of colorectal cancer (CRC) patients: Targeting with inhibitor peptide nucleic acids is …
Simple Summary Starting from a list of nine miRNAs found to be dysregulated in the
bloodstream of early-stage colon cancer (CRC) patients, the biological effects of the …
bloodstream of early-stage colon cancer (CRC) patients, the biological effects of the …
[HTML][HTML] Modulation of AKT pathway-targeting miRNAs for cancer cell treatment with natural products
Many miRNAs are known to target the AKT serine-threonine kinase (AKT) pathway, which is
critical for the regulation of several cell functions in cancer cell development. Many natural …
critical for the regulation of several cell functions in cancer cell development. Many natural …
[HTML][HTML] Combined Treatment of Cancer Cells Using Allyl Palladium Complexes Bearing Purine-Based NHC Ligands and Molecules Targeting MicroRNAs miR-221 …
C Tupini, M Zurlo, J Gasparello, I Lodi, A Finotti… - Pharmaceutics, 2023 - mdpi.com
Combined treatments employing lower concentrations of different drugs are used and
studied to develop new and more effective anticancer therapeutic approaches. The …
studied to develop new and more effective anticancer therapeutic approaches. The …
[HTML][HTML] Synergistic Effects of A Combined Treatment of Glioblastoma U251 Cells with An Anti-miR-10b-5p Molecule and An AntiCancer Agent Based on 1-(3′, 4′, 5 …
(1) Background: In the development of new and more effective anticancer approaches,
combined treatments appear of great interest. Combination therapy could be of importance …
combined treatments appear of great interest. Combination therapy could be of importance …