[HTML][HTML] Epigenetic drivers of tumourigenesis and cancer metastasis

A Chatterjee, EJ Rodger, MR Eccles - Seminars in cancer biology, 2018 - Elsevier
Since the completion of the first human genome sequence and the advent of next generation
sequencing technologies, remarkable progress has been made in understanding the …

Curcumin as a MicroRNA regulator in cancer: a review

AA Momtazi, F Shahabipour, S Khatibi… - Reviews of Physiology …, 2016 - Springer
Curcumin is a natural dietary polyphenol for which anti-tumor effects have been
documented. Anti-inflammatory and antioxidant properties of curcumin, along with its …

Food-borne chemical carcinogens and the evidence for human cancer risk

T Kobets, BPC Smith, GM Williams - Foods, 2022 - mdpi.com
Commonly consumed foods and beverages can contain chemicals with reported
carcinogenic activity in rodent models. Moreover, exposures to some of these substances …

[HTML][HTML] miR-22 inhibits tumor growth and metastasis by targeting ATP citrate lyase: evidence in osteosarcoma, prostate cancer, cervical cancer and lung cancer

M Xin, Z Qiao, J Li, J Liu, S Song, X Zhao, P Miao… - Oncotarget, 2016 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are non-coding small RNAs that function as negative regulators of
gene expression involving in the tumor biology. ATP citrate lyase (ACLY), a key enzyme …

Role of microRNAs in the therapeutic effects of curcumin in non-cancer diseases

AA Momtazi, G Derosa, P Maffioli, M Banach… - Molecular diagnosis & …, 2016 - Springer
Curcumin is a bioactive polyphenol occurring in the rhizomes of Curcuma longa. It is well-
reputed for its chemopreventive and anticancer properties; however, recent evidence has …

Mechanistic understanding of curcumin's therapeutic effects in lung cancer

WNB Wan Mohd Tajuddin, NH Lajis, F Abas, I Othman… - Nutrients, 2019 - mdpi.com
Lung cancer is among the most common cancers with a high mortality rate worldwide.
Despite the significant advances in diagnostic and therapeutic approaches, lung cancer …

Epigenetic mechanisms and cancer: an interface between the environment and the genome

Z Herceg, T Vaissière - Epigenetics, 2011 - Taylor & Francis
Although epidemiological studies support the role of environment in a wide range of human
cancers, the precise mechanisms by which environmental exposures promote cancer …

Histone modifications and cancer

C Sawan, Z Herceg - Advances in genetics, 2010 - Elsevier
It is now widely recognized that epigenetic events are important mechanisms underlying
cancer development and progression. Epigenetic information in chromatin includes covalent …

Epigenetically facilitated mutational assimilation: epigenetics as a hub within the inclusive evolutionary synthesis

E Danchin, A Pocheville, O Rey, B Pujol… - Biological …, 2019 - Wiley Online Library
After decades of debate about the existence of non‐genetic inheritance, the focus is now
slowly shifting towards dissecting its underlying mechanisms. Here, we propose a new …

Cancer chemoprevention and nutri-epigenetics: state of the art and future challenges

C Gerhauser - Natural products in cancer prevention and therapy, 2013 - Springer
The term “epigenetics” refers to modifications in gene expression caused by heritable, but
potentially reversible, changes in DNA methylation and chromatin structure. Epigenetic …