The transcription factor family activator protein 2 (TFAP2) is vital for regulating both
embryonic and oncogenic development. The TFAP2 family consists of five DNA-binding …

Abstract The Activator Protein 2 (AP-2) transcription factor (TF) family is vital for the
regulation of gene expression during early development as well as carcinogenesis process …

Aberrant expression of transcription factor AP-2α has been functionally associated with
various cancers, but its clinical significance and molecular mechanisms in human glioma …

We investigated whether Rad51 overexpression plays a role in soft tissue sarcoma (STS)
chemoresistance as well as the regulatory mechanisms underlying its expression. The …

Abstract Activator protein‐2 (AP‐2) transcription factors are involved in the regulation of cell
proliferation, differentiation, apoptosis and carcinogenesis. AP‐2α has been suggested to …

Background Genetic as well as epigenetic alterations are a hallmark of both epithelial and
haematological malignancies. High throughput screens are required to identify epigenetic …

The transcription factor AP-2α functions as a tumor suppressor by regulating various genes
that are involved in cell proliferation and apoptosis. Chemotherapeutic drugs including …

The events occurring during tumor formation and progression display similarities to some of
the steps in embryonic morphogenesis. The family of AP‐2 proteins consists of five different …

Kahweol is a coffee-specific diterpene found in the beans of Coffea arabica and has been
reported to demonstrate various biological activities, including anti-inflammatory …

Aberrant methylation of the transcription factor AP-2 epsilon (TFAP2E) has been attributed to
5-fluorouridine (5-FU) sensitivity. 5-Aza-2′-deoxycytidine (DAC), an epigenetic drug that …