Serratia species, in particular Serratia marcescens, are significant human pathogens. S.
marcescens has a long and interesting taxonomic, medical experimentation, military …

Extended-spectrum β-lactamases (ESBLs) are a rapidly evolving group of β-lactamases
which share the ability to hydrolyze third-generation cephalosporins and aztreonam yet are …

Extended-spectrum β-lactamases (ESBLs) are a group of plasmid-mediated, diverse,
complex and rapidly evolving enzymes that are posing a major therapeutic challenge today …

SUMMARY β-Lactamases continue to be the leading cause of resistance to β-lactam
antibiotics among gram-negative bacteria. In recent years there has been an increased …

The production of-lactamases is the predominant cause of resistance to-lactam antibiotics in
gram-negative bacteria. These enzymes cleave the amide bond in the-lactam ring …

The β-lactamases are the major bacterial defense of gram-negative bacteria against β-
lactam antibiotics. This review details the many types of β-lactamases, explains how they …

Extended‐spectrum β‐lactamases (ESBLs) represent a major threat among resistant
bacterial isolates. The first types described were derivatives of the TEM‐1, TEM‐2 and SHV …

Abstract β-lactams have a long history in the treatment of infectious diseases, though their
use has been and continues to be confounded by the development of resistance in target …

Nine clinical isolates of Enterobacteriaceae (six Escherichia coli and three Proteus mirabilis)
isolated in three Parisian hospitals between 1989 and 2000 showed a particular extended …

The rapid and irrepressible increase in antimicrobial resistance of pathogenic bacteria that
has been observed over the last two decades is widely accepted to be one of the major …