Coccidioidomycosis: host response and vaccine development
RA Cox, DM Magee - Clinical microbiology reviews, 2004 - Am Soc Microbiol
Coccidioidomycosis is caused by the dimorphic fungi in the genus Coccidioides. These
fungi live as mycelia in the soil of desert areas of the American Southwest, and when the …
fungi live as mycelia in the soil of desert areas of the American Southwest, and when the …
Preclinical and clinical progress of particle-mediated DNA vaccines for infectious diseases
DH Fuller, P Loudon, C Schmaljohn - Methods, 2006 - Elsevier
This review provides an overview of studies employing particle-mediated epidermal delivery
(PMED) or the gene gun to administer DNA vaccines for infectious diseases in preclinical …
(PMED) or the gene gun to administer DNA vaccines for infectious diseases in preclinical …
Soluble mediators of inflammation in HIV and their implications for therapeutics and vaccine development
From early in the HIV epidemic it was appreciated that many inflammatory markers such as
neopterin and TNF-α were elevated in patients with AIDS. With the advent of modern …
neopterin and TNF-α were elevated in patients with AIDS. With the advent of modern …
Enhanced cellular immunity and systemic control of SHIV infection by combined parenteral and mucosal administration of a DNA prime MVA boost vaccine regimen
B Mäkitalo, P Lundholm, J Hinkula… - Journal of general …, 2004 - microbiologyresearch.org
The immunogenicity and protective efficacy of a DNA and recombinant modified vaccinia
Ankara (MVA) vaccine administered by two different routes were investigated. DNA …
Ankara (MVA) vaccine administered by two different routes were investigated. DNA …
The role of particle-mediated DNA vaccines in biodefense preparedness
HJ Dean, J Haynes, C Schmaljohn - Advanced drug delivery reviews, 2005 - Elsevier
Particle-mediated epidermal delivery (PMED) of DNA vaccines is based on the acceleration
of DNA-coated gold directly into the cytoplasm and nuclei of living cells of the epidermis …
of DNA-coated gold directly into the cytoplasm and nuclei of living cells of the epidermis …
Identification of a protective antigen of Coccidioides immitis by expression library immunization
FD Ivey, DM Magee, MD Woitaske, SA Johnston… - Vaccine, 2003 - Elsevier
Coccidioides immitis is a fungal pathogen of humans and is classified as a Select Agent. We
have identified a new potential vaccine candidate for this pathogen using cDNA expression …
have identified a new potential vaccine candidate for this pathogen using cDNA expression …
Expression library immunization to discover and improve vaccine antigens
MA Barry, DPG Howell, HA Andersson… - Immunological …, 2004 - Wiley Online Library
Genetic immunization is a novel method for vaccination in which DNA is delivered into the
host to drive both cellular and humoral immune responses against its protein product. While …
host to drive both cellular and humoral immune responses against its protein product. While …
DNA vaccines and their application against parasites-promise, limitations and potential solutions Peter M. Smooker', Adam Rainczuk², Nicholas Kennedy², and Terry …
PM Smooker, A Rainczuk, N Kennedy… - Biotechnology annual …, 2004 - books.google.com
DNA or nucleic acid vaccines are being evaluated for efficacy against a range of parasitic
diseases. Data from studies in rodent model systems have provided proof of principle that …
diseases. Data from studies in rodent model systems have provided proof of principle that …
Protection against heartwater by DNA immunisation with four Ehrlichia ruminantium open reading frames
A Pretorius, NE Collins, HC Steyn, F Van Strijp… - Vaccine, 2007 - Elsevier
We have reported previously that a recombinant DNA vaccine consisting of four Ehrlichia
ruminantium (Welgevonden) open reading frames (ORFs) known as the 1H12 cocktail …
ruminantium (Welgevonden) open reading frames (ORFs) known as the 1H12 cocktail …
Co-immunization of rhesus macaques with plasmid vectors expressing IFN-γ, GM-CSF, and SIV antigens enhances anti-viral humoral immunity but does not affect …
P Lena, F Villinger, L Giavedoni, CJ Miller, G Rhodes… - Vaccine, 2002 - Elsevier
To investigate the adjuvant capacity of granulocyte-macrophage colony-stimulating factor
(GM-CSF) and interferon (IFN-γ), we cloned these rhesus cytokines into a mammalian …
(GM-CSF) and interferon (IFN-γ), we cloned these rhesus cytokines into a mammalian …