A comprehensive review of microneedles: Types, materials, processes, characterizations and applications

FK Aldawood, A Andar, S Desai - Polymers, 2021 - mdpi.com
Drug delivery through the skin offers many advantages such as avoidance of hepatic first-
pass metabolism, maintenance of steady plasma concentration, safety, and compliance over …

Engineering microneedle patches for improved penetration: analysis, skin models and factors affecting needle insertion

P Makvandi, M Kirkby, ARJ Hutton, M Shabani… - Nano-Micro Letters, 2021 - Springer
Transdermal microneedle (MN) patches are a promising tool used to transport a wide variety
of active compounds into the skin. To serve as a substitute for common hypodermic needles …

Enhancement strategies for transdermal drug delivery systems: Current trends and applications

D Ramadon, MTC McCrudden, AJ Courtenay… - Drug delivery and …, 2021 - Springer
Transdermal drug delivery systems have become an intriguing research topic in
pharmaceutical technology area and one of the most frequently developed pharmaceutical …

Microneedle for transdermal drug delivery: current trends and fabrication

JH Jung, SG Jin - Journal of pharmaceutical investigation, 2021 - Springer
Background Transdermal delivery has the advantage of bypassing the first-pass effect and
allowing sustained release of the drug. However, the drug delivery is limited owing to the …

Microneedle system for tissue engineering and regenerative medicine

Y Zhang, Y Xu, H Kong, J Zhang, HF Chan… - …, 2023 - Wiley Online Library
Global increasing demand for high life quality and length facilitates the development of
tissue engineering and regenerative medicine, which apply multidisciplinary theories and …

[HTML][HTML] Microneedles: A smart approach and increasing potential for transdermal drug delivery system

T Waghule, G Singhvi, SK Dubey, MM Pandey… - Biomedicine & …, 2019 - Elsevier
The most widely used methods for transdermal administration of the drugs are hypodermic
needles, topical creams, and transdermal patches. The effect of most of the therapeutic …

[HTML][HTML] Advanced nanocarrier-and microneedle-based transdermal drug delivery strategies for skin diseases treatment

F Qu, R Geng, Y Liu, J Zhu - Theranostics, 2022 - ncbi.nlm.nih.gov
Skin diseases are the fourth leading cause of nonfatal and chronic skin diseases, acting as a
global burden and affecting the world economy. Skin diseases severely impact the patients' …

3D printing in pharmaceutical and medical applications–recent achievements and challenges

W Jamróz, J Szafraniec, M Kurek, R Jachowicz - Pharmaceutical research, 2018 - Springer
Growing demand for customized pharmaceutics and medical devices makes the impact of
additive manufacturing increased rapidly in recent years. The 3D printing has become one …

Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts

MP Stewart, R Langer, KF Jensen - Chemical reviews, 2018 - ACS Publications
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Zero-order drug delivery: State of the art and future prospects

ML Laracuente, HY Marina, KJ McHugh - Journal of Controlled Release, 2020 - Elsevier
Pharmaceutical drugs are an important part of the global healthcare system, with some
estimates suggesting over 50% of the world's population takes at least one medication per …