Type IV secretion in Gram‐negative and Gram‐positive bacteria

E Grohmann, PJ Christie, G Waksman… - Molecular …, 2018 - Wiley Online Library
Type IV secretion systems (T4SSs) are versatile multiprotein nanomachines spanning the
entire cell envelope in Gram‐negative and Gram‐positive bacteria. They play important …

Bartonella species, an emerging cause of blood-culture-negative endocarditis

U Okaro, A Addisu, B Casanas… - Clinical Microbiology …, 2017 - Am Soc Microbiol
Since the reclassification of the genus Bartonella in 1993, the number of species has grown
from 1 to 45 currently designated members. Likewise, the association of different Bartonella …

Towards an integrated model of bacterial conjugation

E Cabezón, J Ripoll-Rozada, A Peña… - FEMS microbiology …, 2015 - academic.oup.com
Bacterial conjugation is one of the main mechanisms for horizontal gene transfer. It
constitutes a key element in the dissemination of antibiotic resistance and virulence genes to …

Biological diversity of prokaryotic type IV secretion systems

CE Alvarez-Martinez, PJ Christie - Microbiology and Molecular …, 2009 - Am Soc Microbiol
Type IV secretion systems (T4SS) translocate DNA and protein substrates across prokaryotic
cell envelopes generally by a mechanism requiring direct contact with a target cell. Three …

[HTML][HTML] Mechanism and structure of the bacterial type IV secretion systems

PJ Christie, N Whitaker, C González-Rivera - Biochimica et Biophysica Acta …, 2014 - Elsevier
The bacterial type IV secretion systems (T4SSs) translocate DNA and protein substrates to
bacterial or eukaryotic target cells generally by a mechanism dependent on direct cell-to-cell …

Biogenesis, architecture, and function of bacterial type IV secretion systems

PJ Christie, K Atmakuri, V Krishnamoorthy… - Annu. Rev …, 2005 - annualreviews.org
Abstract Type IV secretion (T4S) systems are ancestrally related to bacterial conjugation
machines. These systems assemble as a translocation channel, and often also as a surface …

Intruders below the radar: molecular pathogenesis of Bartonella spp

A Harms, C Dehio - Clinical microbiology reviews, 2012 - Am Soc Microbiol
Bartonella spp. are facultative intracellular pathogens that employ a unique stealth infection
strategy comprising immune evasion and modulation, intimate interaction with nucleated …

Type IV secretion systems and their effectors in bacterial pathogenesis

S Backert, TF Meyer - Current opinion in microbiology, 2006 - Elsevier
Type IV secretion systems (T4SSs) are membrane-associated transporter complexes used
by various bacteria to deliver substrate molecules to a wide range of target cells. T4SSs are …

[HTML][HTML] Ecological fitness and strategies of adaptation of Bartonella species to their hosts and vectors

BB Chomel, HJ Boulouis, EB Breitschwerdt… - Veterinary …, 2009 - ncbi.nlm.nih.gov
Bartonella spp. are facultative intracellular bacteria that cause characteristic host-restricted
hemotropic infections in mammals and are typically transmitted by blood-sucking …

[HTML][HTML] c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains

D Mueller, N Tegtmeyer, S Brandt… - The Journal of …, 2012 - Am Soc Clin Investig
Many bacterial pathogens inject into host cells effector proteins that are substrates for host
tyrosine kinases such as Src and Abl family kinases. Phosphorylated effectors eventually …